Researcher Profile

Researcher Profile

John Patrick Vanden Heuvel, PhD

John Patrick Vanden Heuvel, PhD

Professor of Veterinary Science, Veterinary and Biomedical Sciences
Scientific Program:Cancer Control

Research Interests

  • Peroxisome Proliferator-Activated Receptors
  • Genes
  • Fatty Acids
  • Liver
  • Gene Expression
  • Proteins
  • Conjugated Linoleic Acids
  • Messenger RNA
  • Peroxisome Proliferators
  • Ligands
  • Cytoplasmic and Nuclear Receptors
  • perfluorodecanoic acid

Recent Publications


Castillo Meza, L, Piotrowski, P, Farnan, J, Tasker, TL, Xiong, B, Weggler, B, Murrell, K, Dorman, FL, Vanden Heuvel, JP & Burgos, WD 2020, 'Detection and removal of biologically active organic micropollutants from hospital wastewater', Science of the Total Environment, vol. 700, 134469.


Liu, X, Garban, J, Jones, PJ, Heuvel, JV, Lamarche, B, Jenkins, DJ, Connelly, PW, Couture, P, Pu, S, Fleming, JA, West, SG & Kris-Etherton, PM 2018, 'Diets low in saturated fat with different unsaturated fatty acid profiles similarly increase serum-mediated cholesterol efflux from THP-1 macrophages in a population with or at risk for metabolic syndrome: The Canola Oil Multicenter Intervention Trial', Journal of Nutrition, vol. 148, no. 5, pp. 721-728.
Tasker, TL, Burgos, WD, Piotrowski, P, Castillo-Meza, L, Blewett, TA, Ganow, KB, Stallworth, A, Delompré, PLM, Goss, GG, Fowler, LB, Vanden Heuvel, JP, Dorman, F & Warner, NR 2018, 'Environmental and Human Health Impacts of Spreading Oil and Gas Wastewater on Roads', Environmental Science and Technology, vol. 52, no. 12, pp. 7081-7091.
Reproducibility Project: Cancer Biology 2018, 'Replication study: Systematic identification of genomic markers of drug sensitivity in cancer cells', eLife, vol. 7, e29747.


Hannon, DB, Thompson, JT, Khoo, C, Juturu, V & Vanden Heuvel, JP 2017, 'Effects of cranberry extracts on gene expression in THP-1 cells', Food Science and Nutrition, vol. 5, no. 1, pp. 148-159.


Hinds, TD, Burns, KA, Hosick, PA, McBeth, L, Nestor-Kalinoski, A, Drummond, HA, Alamodi, AA, Hankins, MW, Vanden Heuvel, JP & Stec, DE 2016, 'Biliverdin reductase A attenuates hepatic steatosis by inhibition of Glycogen Synthase Kinase (GSK) 3β phosphorylation of serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α', Journal of Biological Chemistry, vol. 291, no. 48, pp. 25179-25191.
Gillies, PJ & Vanden Heuvel, JP 2016, Nutrigenomic approaches to unraveling the physiological effects of complex foods. in Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition. CRC Press, pp. 105-115.
Reproducibility Project: Cancer Biology 2016, 'Registered report: Systematic identification of genomic markers of drug sensitivity in cancer cells', eLife, vol. 5, no. JUNE2016, e13620.
Smith, RW, Coleman, JD, Thompson, JT & Vanden Heuvel, JP 2016, 'Therapeutic potential of GW501516 and the role of Peroxisome proliferator-activated receptor β/δ and B-cell lymphoma 6 in inflammatory signaling in human pancreatic cancer cells', Biochemistry and Biophysics Reports, vol. 8, pp. 395-402.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)