Researcher Profile

Researcher Profile

Helen Marie Kamens, PhD

Helen Marie Kamens, PhD

Broadhurst Career Development Professor for the Study of Health Promotion and Disease Prevention and Assistant Professor, Biobehavioral Health
Penn State Neuroscience Institute
Scientific Program:Cancer Control

Research Interests

  • Ethanol
  • Nicotinic Receptors
  • Nicotine
  • Genes
  • Pharmaceutical Preparations
  • Inbred C57BL Mouse
  • Methamphetamine
  • Substance-Related Disorders
  • Inbred DBA Mouse
  • Ataxia
  • Gene Expression
  • Alcohols

Recent Publications


Kamens, HM, Silva, CP, Nye, RT, Miller, CN, Singh, N, Sipko, J, Trushin, N, Sun, D, Branstetter, SA, Muscat, JE, Richie, JP & Foulds, J 2020, 'Pharmacokinetic Profile of Spectrum Reduced Nicotine Cigarettes', Nicotine and Tobacco Research, vol. 22, no. 2, pp. 273-279.


Miller, CN, Caruso, MJ & Kamens, HM 2019, 'Corrigendum to “Early-adolescent male C57BL/6J and DBA/2J mice display reduced sensitivity to acute nicotine administration” [Neurosci. Lett. 690 (2019) 151–157](S0304394018306906)(10.1016/j.neulet.2018.10.014)', Neuroscience letters, vol. 707, 134307.
Miller, CN, Caruso, MJ & Kamens, HM 2019, 'Early-adolescent male C57BL/6J and DBA/2J mice display reduced sensitivity to acute nicotine administration', Neuroscience letters, vol. 690, pp. 151-157.
Miller, CN & Kamens, HM 2020, 'Reduced expression of ethanol sensitization by α3β4 nicotinic acetylcholine receptors in DBA/2J mice', Experimental and clinical psychopharmacology, vol. 28, no. 3, pp. 348-354.
Miller, CN, Ruggery, C & Kamens, HM 2019, 'The α3β4 nicotinic acetylcholine receptor antagonist 18-Methoxycoronaridine decreases binge-like ethanol consumption in adult C57BL/6J mice', Alcohol, vol. 79, pp. 1-6.


Caruso, MJ, Crowley, N, Reiss, DE, Caulfield, JI, Luscher, B, Cavigelli, SA & Kamens, HM 2018, 'Adolescent Social Stress Increases Anxiety-like Behavior and Alters Synaptic Transmission, Without Influencing Nicotine Responses, in a Sex-Dependent Manner', Neuroscience, vol. 373, pp. 182-198.
Caruso, MJ, Seemiller, LR, Fetherston, TB, Miller, CN, Reiss, DE, Cavigelli, SA & Kamens, HM 2018, 'Adolescent social stress increases anxiety-like behavior and ethanol consumption in adult male and female C57BL/6J mice', Scientific reports, vol. 8, no. 1, 10040.
Silva, CP, Horton, WJ, Caruso, MJ, Sebastian, A, Klein, LC, Albert, I & Kamens, HM 2018, 'The influence of adolescent nicotine exposure on ethanol intake and brain gene expression', PloS one, vol. 13, no. 6, e0198935.


Caruso, MJ, Reiss, DE, Caulfield, JI, Thomas, JL, Baker, AN, Cavigelli, SA & Kamens, HM 2018, 'Adolescent chronic variable social stress influences exploratory behavior and nicotine responses in male, but not female, BALB/cJ mice', Brain Research Bulletin, vol. 138, pp. 37-49.
Caruso, MJ, Kamens, HM & Cavigelli, SA 2017, 'Exposure to chronic variable social stress during adolescence alters affect-related behaviors and adrenocortical activity in adult male and female inbred mice', Developmental psychobiology, vol. 59, no. 6, pp. 679-687.
Kamens, HM, Silva, C, McCarthy, R, Cox, RJ & Ehringer, MA 2017, 'No evidence of a role of the β4 subunit of the nicotinic acetylcholine receptor in alcohol-related behaviors', BMC Research Notes, vol. 10, no. 1, 151.
Kamens, HM, Silva, C, Peck, C & Miller, CN 2018, 'Varenicline modulates ethanol and saccharin consumption in adolescent male and female C57BL/6J mice', Brain Research Bulletin, vol. 138, pp. 20-25.


Schwantes-An, TH, Zhang, J, Chen, LS, Hartz, SM, Culverhouse, RC, Chen, X, Coon, H, Frank, J, Kamens, HM, Konte, B, Kovanen, L, Latvala, A, Legrand, LN, Maher, BS, Melroy, WE, Nelson, EC, Reid, MW, Robinson, JD, Shen, PH, Yang, BZ, Andrews, JA, Aveyard, P, Beltcheva, O, Brown, SA, Cannon, DS, Cichon, S, Corley, RP, Dahmen, N, Degenhardt, L, Foroud, T, Gaebel, W, Giegling, I, Glatt, SJ, Grucza, RA, Hardin, J, Hartmann, AM, Heath, AC, Herms, S, Hodgkinson, CA, Hoffmann, P, Hops, H, Huizinga, D, Ising, M, Johnson, EO, Johnstone, E, Kaneva, RP, Kendler, KS, Kiefer, F, Kranzler, HR, Krauter, KS, Levran, O, Lucae, S, Lynskey, MT, Maier, W, Mann, K, Martin, NG, Mattheisen, M, Montgomery, GW, Müller-Myhsok, B, Murphy, MF, Neale, MC, Nikolov, MA, Nishita, D, Nöthen, MM, Nurnberger, J, Partonen, T, Pergadia, ML, Reynolds, M, Ridinger, M, Rose, RJ, Rouvinen-Lagerström, N, Scherbaum, N, Schmäl, C, Soyka, M, Stallings, MC, Steffens, M, Treutlein, J, Tsuang, M, Wall, TL, Wodarz, N, Yuferov, V, Zill, P, Bergen, AW, Chen, J, Cinciripini, PM, Edenberg, HJ, Ehringer, MA, Ferrell, RE, Gelernter, J, Goldman, D, Hewitt, JK, Hopfer, CJ, Iacono, WG, Kaprio, J, Kreek, MJ, Kremensky, IM, Madden, PAF, McGue, M, Munafò, MR, Philibert, RA, Rietschel, M, Roy, A, Rujescu, D, Saarikoski, ST, Swan, GE, Todorov, AA, Vanyukov, MM, Weiss, RB, Bierut, LJ & Saccone, NL 2016, 'Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts', Behavior Genetics, vol. 46, no. 2, pp. 151-169.
Kamens, HM, Corley, RP, Richmond, PA, Darlington, TM, Dowell, R, Hopfer, CJ, Stallings, MC, Hewitt, JK, Brown, SA & Ehringer, MA 2016, 'Evidence for Association Between Low Frequency Variants in CHRNA6/CHRNB3 and Antisocial Drug Dependence', Behavior Genetics, vol. 46, no. 5, pp. 693-704.
Locker, AR, Marks, MJ, Kamens, HM & Klein, LC 2016, 'Exposure to nicotine increases nicotinic acetylcholine receptor density in the reward pathway and binge ethanol consumption in C57BL/6J adolescent female mice', Brain Research Bulletin, vol. 123, pp. 13-22.
Melroy-Greif, WE, Vadasz, C, Kamens, HM, McQueen, MB, Corley, RP, Stallings, MC, Hopfer, CJ, Krauter, KS, Brown, SA, Hewitt, JK & Ehringer, MA 2016, 'Test for association of common variants in GRM7 with alcohol consumption', Alcohol, vol. 55, pp. 43-50.
Kamens, HM, Peck, C, Garrity, C, Gechlik, A, Jenkins, BC & Rajan, A 2017, 'α6β2 nicotinic acetylcholine receptors influence locomotor activity and ethanol consumption', Alcohol, vol. 61, pp. 43-49.

Clinical Trials Search

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Adults (age >= 18 years)