Researcher Profile

Researcher Profile

Heath Mackley, MD

Heath Mackley, MD

Associate Professor, Department of Radiation Oncology
Associate Professor, Department of Medicine
Associate Professor, Department of Pediatrics
Associate Professor, Department of Radiology
Scientific Program:Experimental Therapeutics
Disease Teams:
Bone Marrow Transplantation
Central Nervous System Cancer
Gastrointestinal Cancer
Genitourinary Cancer
Head and Neck Cancer
Leukemia and Lymphoma
Liver, Pancreas and Foregut Cancer
Melanoma and Skin Cancer
Pediatric Cancer
Sarcoma Cancer

Research Interests

  • Therapeutics
  • Neoplasms
  • Radiotherapy
  • Radiation
  • Survival
  • Colorectal Neoplasms
  • Melanoma
  • Drug Therapy
  • Appalachian Region
  • Breast Neoplasms
  • Mouth Neoplasms
  • Mouth

Clinical Trials

Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1-21 years
A Randomized Phase II Trial of Brentuximab Vedotin (SGN35, NSC# 749710), or Crizotinib (NSC#749005, Commercially Labeled) in Combination With Chemotherapy for Newly Diagnosed Patients With Anaplastic Large Cell Lymphoma (ALCL)

Recent Publications




Liu, J, Goldenberg, D, Almokadem, S, Crist, H & Mackley, H 2017, 'Long-term recurrence-free survival after an unplanned reduction in radiotherapy for HPV-positive oropharyngeal SCC: Two cases and a review of the literature' Ear, Nose and Throat Journal, vol. 96, no. 7, E23.


Baker, A, Camacho, F, Andrews, GA & Mackley, H 2016, 'A retrospective analysis of the role of adjuvant radiotherapy in the treatment of cutaneous melanoma', Cancer Biology and Therapy, vol. 17, no. 10, pp. 1030-1034.
Al-Marrawi, MY, Mackley, H, Ali, S, Wagner Jr., H, Joshi, M, Holder, S, Kaag, MG, Mallon, C, Talamo, G & Drabick, J 2016, 'Consolidation With Radiation or Concurrent Chemo-Radiation After Chemotherapy Results in Durable Complete Remissions of Isolated Nodal Recurrences of Urothelial Cancer: A Case Series and Review', Clinical Genitourinary Cancer, vol. 14, no. 4, pp. e393-e399.


Wyluda, EJ, Cheng, J, Schell, T, Haley, JS, Mallon, C, Neves, R, Robertson, G, Sivik, J, Mackley, H, Talamo, G & Drabick, J 2015, 'Durable complete responses off all treatment in patients with metastatic malignant melanoma after sequential immunotherapy followed by a finite course of BRAF inhibitor therapy', Cancer Biology and Therapy, vol. 16, no. 5, pp. 662-670.
Kimmick, GG, Camacho, F, Mackley, H, Kern, T, Yao, N, Matthews, SA, Fleming, S, Lipscomb, J, Liao, JJ, Hwang, W & Anderson, RT 2015, 'Individual, area, and provider characteristics associated with care received for stages I to III breast cancer in a multistate region of Appalachia', Journal of oncology practice, vol. 11, no. 1, pp. e9-e18.
Hess, CB, Singer, M, Khaku, A, Malinou, J, Juliano, JJ, Varlotto, JM, Wagner Jr., H, Liao, JJ, Myers, K, Levine, M & Mackley, H 2015, 'Optimal frequency of psychosocial distress screening in radiation oncology', Journal of oncology practice, vol. 11, no. 4, pp. 298-302.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)