Gayle Smink, MD, MPH - Penn State Cancer Institute
Researcher Profile
Gayle Smink, MD, MPH
Associate Professor, Department of Pediatrics
Disease Teams:
Cancer Institute, Pediatric Cancer Team
Clinical Trials
A Phase 3 Randomized Controlled Trial Comparing Open vs Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Phase II Trial of Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma BCC022
ACCL1931: A Randomized Trial of Levocarnitine Prophylaxis to Prevent Asparaginase-Associated Hepatotoxicity in Adolescents and Young Adults Receiving Acute Lymphoblastic Leukemia Therapy
A Dose Escalation Study Using Difluoromethylornithine (DFMO) and AMXT-1501 followed by a Randomized Controlled Trial of DFMO with or without AMXT-1501 for Neuroblastoma, CNS Tumors, and Sarcomas
BCC021 Phase I/II study of Silmitasertib (CX-4945) in combination with chemotherapy in children and young adults with relapsed refractory solid tumors
Pediatric Acute Leukemia (PedAL) Screening Trial Developing New Therapies for Relapsed Leukemias
A Prospective Phase 3 Study of Patients with Newly Diagnosed Very Low-risk and Low-risk Fusion Negative Rhabdomyosarcoma
AHOD2131 A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy with Immuno-oncology Therapy for Children and Adults with Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma
Recent Publications
2025
Sisk, BA, Eng, W, Aye, J, Mack, J, Tran, A, Ogino, J, Pearson, E, Bies, J, Smink, G, Shah, SD, Mohney, L, Fassel, H, Schulte, R, Chang, VY, Tessem, RA, Hogeling, M, Swaminathan, N, McLean, TW, Blatt, J, Alturky, S, Wu, M, Atkinson, A, Al-Huniti, A, Massey, G, Engel, E, Ricci, K, Echols, T, Kumar, S, Fox, M & King, KA 2025, 'Sociodemographic Characteristics of Patients Seen at Vascular Anomaly Centers in the United States', Pediatric Blood and Cancer, vol. 72, no. 6, e31661. https://doi.org/10.1002/pbc.31661
2024
Gay, K, Smink, G, Mulieri, K & Dandekar, S 2024, 'Delayed serum sickness reaction after initial hypersensitivity reaction to calaspargase during treatment for B-cell acute lymphoblastic leukemia', Pediatric Blood and Cancer, vol. 71, no. 5, e30922. https://doi.org/10.1002/pbc.30922
Kuntz, H, Santucci, J, Butts, S, Dandekar, S, Smink, G, Van Scoy, LJ & Rao, P 2024, 'Determinants of Decision Regret Regarding Fertility Preservation in Adolescent and Young Adult Cancer Survivors: A Systematic Review', Journal of Adolescent and Young Adult Oncology, vol. 13, no. 5, pp. 726-737. https://doi.org/10.1089/jayao.2023.0191
Caru, M, Dandekar, S, Gordon, B, Conroy, DE, Barb, ED, Doerksen, SE, Smink, GM, McKeone, DJ, Shah, NB, Greiner, RJ, Schramm, JW, Rao, P, McGregor, L & Schmitz, KH 2024, 'Implementing a behavioral physical activity program in children and adolescent survivors of childhood cancer: a pilot randomized controlled trial', Journal of Behavioral Medicine, vol. 47, no. 5, pp. 792-803. https://doi.org/10.1007/s10865-024-00497-z
2021
McGrath, M & Smink, G 2021, 'Double and single mixed-lineage leukemia-rearranged subclones in pediatric acute myeloid leukemia: a case report', Journal of Medical Case Reports, vol. 15, no. 1, 228. https://doi.org/10.1186/s13256-021-02841-2