Researcher Profile

Researcher Profile

Jiafen Hu, MSc, PhD

Jiafen Hu, MSc, PhD

Assistant Professor, Department of Pathology and Laboratory Medicine
Division of Experimental Pathology
Scientific Program:Mechanisms of Carcinogenesis
fjh4@psu.edu

Research Interests

  • Rabbits
  • Cottontail rabbit papillomavirus
  • Papillomavirus Infections
  • Immunity
  • Infections
  • Papilloma
  • DNA
  • Neoplasms
  • Vaccination
  • Genome
  • Skin
  • Epitopes

Recent Publications

2022

Hu, J, Brendle, SA, Li, JJ, Walter, V, Cladel, NM, Cooper, T, Shearer, DA, Balogh, KK & Christensen, N 2022, 'Depo Medroxyprogesterone (DMPA) Promotes Papillomavirus Infections but Does Not Accelerate Disease Progression in the Anogenital Tract of a Mouse Model', Viruses, vol. 14, no. 5, 980. https://doi.org/10.3390/v14050980

2021

Brendle, S, Cladel, N, Balogh, K, Alam, S, Christensen, N, Meyers, C & Hu, J 2021, 'A comparative study on delivery of externally attached dna by papillomavirus vlps and pseudoviruses', Vaccines, vol. 9, no. 12, 1501. https://doi.org/10.3390/vaccines9121501
Hartmann, SR, Goetschius, DJ, Hu, J, Graff, JJ, Bator, CM, Christensen, ND & Hafenstein, SL 2021, 'Cryo em analysis reveals inherent flexibility of authentic murine papillomavirus capsids', Viruses, vol. 13, no. 10, 2023. https://doi.org/10.3390/v13102023
Xu, J, Zhang, J, Yang, D, Song, J, Pallas, B, Zhang, C, Hu, J, Peng, X, Christensen, ND, Han, R & Chen, YE 2021, 'Gene Editing in Rabbits: Unique Opportunities for Translational Biomedical Research', Frontiers in Genetics, vol. 12, 642444. https://doi.org/10.3389/fgene.2021.642444
Béziat, V, Rapaport, F, Hu, J, Titeux, M, Bonnet des Claustres, M, Bourgey, M, Griffin, H, Bandet, É, Ma, CS, Sherkat, R, Rokni-Zadeh, H, Louis, DM, Changi-Ashtiani, M, Delmonte, OM, Fukushima, T, Habib, T, Guennoun, A, Khan, T, Bender, N, Rahman, M, About, F, Yang, R, Rao, G, Rouzaud, C, Li, J, Shearer, D, Balogh, K, Al Ali, F, Ata, M, Dabiri, S, Momenilandi, M, Nammour, J, Alyanakian, MA, Leruez-Ville, M, Guenat, D, Materna, M, Marcot, L, Vladikine, N, Soret, C, Vahidnezhad, H, Youssefian, L, Saeidian, AH, Uitto, J, Catherinot, É, Navabi, SS, Zarhrate, M, Woodley, DT, Jeljeli, M, Abraham, T, Belkaya, S, Lorenzo, L, Rosain, J, Bayat, M, Lanternier, F, Lortholary, O, Zakavi, F, Gros, P, Orth, G, Abel, L, Prétet, JL, Fraitag, S, Jouanguy, E, Davis, MM, Tangye, SG, Notarangelo, LD, Marr, N, Waterboer, T, Langlais, D, Doorbar, J, Hovnanian, A, Christensen, N, Bossuyt, X, Shahrooei, M & Casanova, JL 2021, 'Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy', Cell, vol. 184, no. 14, pp. 3812-3828.e30. https://doi.org/10.1016/j.cell.2021.06.004
Brendle, S, Li, JJ, Cladel, NM, Shearer, DA, Budgeon, LR, Balogh, KK, Atkins, H, Costa-Fujishima, M, Lopez, P, Christensen, ND, Doorbar, J, Murooka, TT & Hu, J 2021, 'Mouse papillomavirus l1 and l2 are dispensable for viral infection and persistence at both cutaneous and mucosal tissues', Viruses, vol. 13, no. 9, 1824. https://doi.org/10.3390/v13091824

2020

El-Bayoumy, K, Christensen, ND, Hu, J, Viscidi, R, Stairs, DB, Walter, V, Chen, KM, Sun, YW, Muscat, JE & Richie, JP 2020, 'An integrated approach for preventing oral cavity and oropharyngeal cancers: Two etiologies with distinct and shared mechanisms of carcinogenesis', Cancer Prevention Research, vol. 13, no. 8, pp. 649-660. https://doi.org/10.1158/1940-6207.CAPR-20-0096
Osborne, AJ, Atkins, HM, Balogh, KK, Brendle, SA, Shearer, DA, Hu, J, Sample, CE & Christensen, ND 2020, 'Antibody-mediated immune subset depletion modulates the immune response in a rabbit (Oryctolagus cuniculus) model of Epstein-Barr virus infection', Comparative Medicine, vol. 70, no. 5, pp. 312-322. https://doi.org/10.30802/AALAS-CM-20-000019
Christensen, ND, Chen, KM, Hu, J, Stairs, DB, Sun, YW, Aliaga, C, Balogh, KK, Atkins, H, Shearer, D, Li, J, Brendle, SA, Gowda, K, Amin, S, Walter, V, Viscidi, R & El-Bayoumy, K 2021, 'The environmental pollutant and tobacco smoke constituent dibenzo[def,p]chrysene is a co-factor for malignant progression of mouse oral papillomavirus infections', Chemico-Biological Interactions, vol. 333, 109321. https://doi.org/10.1016/j.cbi.2020.109321

2019

Esteves, PJ, Abrantes, J, Baldauf, HM, BenMohamed, L, Chen, Y, Christensen, N, González-Gallego, J, Giacani, L, Hu, J, Kaplan, G, Keppler, OT, Knight, KL, Kong, XP, Lanning, DK, Le Pendu, J, de Matos, AL, Liu, J, Liu, S, Lopes, AM, Lu, S, Lukehart, S, Manabe, YC, Neves, F, McFadden, G, Pan, R, Peng, X, de Sousa-Pereira, P, Pinheiro, A, Rahman, M, Ruvoën-Clouet, N, Subbian, S, Tuñón, MJ, van der Loo, W, Vaine, M, Via, LE, Wang, S & Mage, R 2019, 'Author Correction: The wide utility of rabbits as models of human diseases (Experimental & Molecular Medicine, (2018), 50, 5, (66), 10.1038/s12276-018-0094-1)', Experimental and Molecular Medicine, vol. 51, no. 7, 71. https://doi.org/10.1038/s12276-019-0252-0
Cladel, NM, Jiang, P, Li, JJ, Peng, X, Cooper, TK, Majerciak, V, Balogh, KK, Meyer, TJ, Brendle, SA, Budgeon, LR, Shearer, DA, Munden, R, Cam, M, Vallur, R, Christensen, ND, Zheng, ZM & Hu, J 2019, 'Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models', Emerging Microbes and Infections, vol. 8, no. 1, pp. 1108-1121. https://doi.org/10.1080/22221751.2019.1637072
Cladel, NM, Peng, X, Christensen, N & Hu, J 2019, 'The rabbit papillomavirus model: A valuable tool to study viral-host interactions', Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 374, no. 1773, 20180294. https://doi.org/10.1098/rstb.2018.0294

2018

Esteves, PJ, Abrantes, J, Baldauf, HM, BenMohamed, L, Chen, Y, Christensen, N, González-Gallego, J, Giacani, L, Hu, J, Kaplan, G, Keppler, OT, Knight, KL, Kong, XP, Lanning, DK, Le Pendu, J, De Matos, AL, Liu, J, Liu, S, Lopes, AM, Lu, S, Lukehart, S, Manabe, YC, Neves, F, McFadden, G, Pan, R, Peng, X, de Sousa-Pereira, P, Pinheiro, A, Rahman, M, Ruvoën-Clouet, N, Subbian, S, Tuñón, MJ, van der Loo, W, Vaine, M, Via, LE, Wang, S & Mage, R 2018, 'The wide utility of rabbits as models of human diseases', Experimental and Molecular Medicine, vol. 50, no. 5, 66. https://doi.org/10.1038/s12276-018-0094-1

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)