David D. Boehr, PhD - Penn State Cancer Institute
Researcher Profile
David D. Boehr, PhD
Professor of Chemistry, Chemistry
Scientific Program:Mechanisms of Carcinogenesis
Recent Publications
2026
D'Amico, RN, Mondal, S, Winston, DS & Boehr, DD 2026, 'Solution-state nuclear magnetic resonance studies of the Salmonella typhimurium tryptophan synthase complex', Biochemistry and Biophysics Reports, vol. 46, 102586. https://doi.org/10.1016/j.bbrep.2026.102586
Sarvari, G & Boehr, DD 2026, 'Structure, Function and Inhibition of Helicases Involved in Virus Infection', Biomolecules, vol. 16, no. 2, 273. https://doi.org/10.3390/biom16020273
2025
Yu, J, Winston, DS & Boehr, DD 2025, 'Molecular determinants of picornavirus 3C protease binding to phosphoinositide-enriched lipid membranes', Journal of Biological Chemistry, vol. 301, no. 9, 110543. https://doi.org/10.1016/j.jbc.2025.110543
Khan, S & Boehr, DD 2025, 'Multi-Enzyme Synergy and Allosteric Regulation in the Shikimate Pathway: Biocatalytic Platforms for Industrial Applications', Catalysts, vol. 15, no. 8, 718. https://doi.org/10.3390/catal15080718
Mondal, S, Mukherjee, S, Namitz, KEW, Yennawar, NH & Boehr, DD 2025, 'Multivalent Interactions Between the Picornavirus 3C(D) Main Protease and RNA Oligonucleotides Induce Liquid–Liquid Phase Separation', Viruses, vol. 17, no. 11, 1473. https://doi.org/10.3390/v17111473
2024
Boehr, DD 2024, 'Editorial: Allosteric functions and inhibitions: structural insights', Frontiers in Molecular Biosciences, vol. 11, 1363100. https://doi.org/10.3389/fmolb.2024.1363100
2023
D'Amico, RN & Boehr, DD 2023, 'Allostery, engineering and inhibition of tryptophan synthase', Current Opinion in Structural Biology, vol. 82, 102657. https://doi.org/10.1016/j.sbi.2023.102657
Mondal, S, Sarvari, G & Boehr, DD 2023, 'Picornavirus 3C Proteins Intervene in Host Cell Processes through Proteolysis and Interactions with RNA', Viruses, vol. 15, no. 12, 2413. https://doi.org/10.3390/v15122413
Yu, J & Boehr, DD 2023, 'Regulatory mechanisms triggered by enzyme interactions with lipid membrane surfaces', Frontiers in Molecular Biosciences, vol. 10, 1306483. https://doi.org/10.3389/fmolb.2023.1306483
2022
Winston, DS & Boehr, DD 2022, 'Catalyst-Based Biomolecular Logic Gates', Catalysts, vol. 12, no. 7, 712. https://doi.org/10.3390/catal12070712
Winston, DS, Gorman, SD & Boehr, DD 2022, 'Conformational Transitions in Yeast Chorismate Mutase Important for Allosteric Regulation as Identified by Nuclear Magnetic Resonance Spectroscopy', Journal of Molecular Biology, vol. 434, no. 17, 167531. https://doi.org/10.1016/j.jmb.2022.167531
Topakas, E, Boehr, D & Wohlgemuth, R 2022, 'Special Issue “10th Anniversary of Catalysts: Biocatalysis in Analysis and Synthesis—Past, Present and Future”', Catalysts, vol. 12, no. 12, 1626. https://doi.org/10.3390/catal12121626