Researcher Profile

Researcher Profile

Cheng Dong, PhD

Cheng Dong, PhD

Department Head and Distinguished Professor, Biomedical Engineering
Scientific Program:Next-Generation Therapies

Research Interests

  • Neoplasms
  • Melanoma
  • Leukocytes
  • Neutrophils
  • Cell Adhesion
  • Neoplasm Metastasis
  • Endothelial Cells
  • Intercellular Adhesion Molecule-1
  • Endothelium
  • Integrins
  • Interleukin-8
  • Pseudopodia

Recent Publications


Kim, GB, Aragon-Sanabria, V, Randolph, L, Jiang, H, Reynolds, JA, Webb, BS, Madhankumar, A, Lian, X, Connor, JR, Yang, J & Dong, C 2020, 'High-affinity mutant Interleukin-13 targeted CAR T cells enhance delivery of clickable biodegradable fluorescent nanoparticles to glioblastoma', Bioactive Materials, vol. 5, no. 3, pp. 624-635.


He, Y, Li, Q, Ma, C, Xie, D, Li, L, Zhao, Y, Shan, D, Chomos, SK, Dong, C, Tierney, JW, Sun, L, Lu, D, Gui, L & Yang, J 2019, 'Development of osteopromotive poly (octamethylene citrate glycerophosphate) for enhanced bone regeneration', Acta Biomaterialia, vol. 93, pp. 180-191.


Ye, K, Kaplan, DL, Bao, G, Bettinger, C, Forgacs, G, Dong, C, Khademhosseini, A, Ke, Y, Leong, K, Sambanis, A, Sun, W & Yin, P 2018, 'Advanced Cell and Tissue Biomanufacturing', ACS Biomaterials Science and Engineering, vol. 4, no. 7, pp. 2292-2307.
Aragon-Sanabria, V, Kim, GB & Dong, C 2018, From cancer immunoediting to new strategies in cancer immunotherapy: The roles of immune cells and mechanics in oncology. in Advances in Experimental Medicine and Biology. Advances in Experimental Medicine and Biology, vol. 1092, Springer New York LLC, pp. 113-138.
Sanabria, VA & Dong, C 2018, 'Integration of biochemical and biomechanical signals regulating endothelial barrier function', MCB Molecular and Cellular Biomechanics, vol. 15, no. 1, pp. 1-19.
Dong, C, Zahir, N & Konstantopoulos, K 2018, 'Preface', Advances in experimental medicine and biology, vol. 1092, pp. v-vi.
Kim, GB, Chen, Y, Kang, W, Guo, J, Payne, R, Li, H, Wei, Q, Baker, J, Dong, C, Zhang, S, Wong, PK, Rizk, EB, Yan, J & Yang, J 2018, 'The critical chemical and mechanical regulation of folic acid on neural engineering', Biomaterials, vol. 178, pp. 504-516.


Tang, X, Loc, WS, Dong, C, Matters, GL, Butler, PJ, Kester, M, Meyers, C, Jiang, Y & Adair, JH 2017, 'The use of nanoparticulates to treat breast cancer', Nanomedicine, vol. 12, no. 19, pp. 2367-2388.
Aragon-Sanabria, V, Pohler, SE, Eswar, VJ, Bierowski, M, Gomez, EW & Dong, C 2017, 'VE-Cadherin Disassembly and Cell Contractility in the Endothelium are Necessary for Barrier Disruption Induced by Tumor Cells', Scientific reports, vol. 7, 45835.


Zhang, P, Feng, S, Liu, G, Wang, H, Fu, A, Zhu, H, Ren, Q, Wang, B, Xu, X, Bai, H & Dong, C 2016, 'CD82 suppresses CD44 alternative splicing-dependent melanoma metastasis by mediating U2AF2 ubiquitination and degradation', Oncogene, vol. 35, no. 38, pp. 5056-5069.
Xie, Z, Su, Y, Kim, GB, Selvi, E, Ma, C, Aragon-Sanabria, V, Hsieh, JT, Dong, C & Yang, J 2017, 'Immune Cell-Mediated Biodegradable Theranostic Nanoparticles for Melanoma Targeting and Drug Delivery', Small, vol. 13, no. 10, 1603121.
Zhang, P, Feng, S, Liu, G, Wang, H, Zhu, H, Ren, Q, Bai, H, Fu, C & Dong, C 2016, 'Mutant B-Raf(V600E) promotes melanoma paracellular transmigration by inducing thrombin-mediated endothelial junction breakdown', Journal of Biological Chemistry, vol. 291, no. 5, pp. 2087-2106.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)