Researcher Profile

Researcher Profile

Cheng Dong, PhD

Cheng Dong, PhD

Department Head and Distinguished Professor, Biomedical Engineering
Scientific Program:Next-Generation Therapies
cxd23@psu.edu

Research Interests

  • Neoplasms
  • Melanoma
  • Leukocytes
  • Cell Adhesion
  • Neutrophils
  • Neoplasm Metastasis
  • Endothelial Cells
  • Intercellular Adhesion Molecule-1
  • Endothelium
  • Integrins
  • Pseudopodia
  • Interleukin-8

Recent Publications

2021

Fu, Y, Li, A, Wu, J, Kunz, RF, Sun, R, Ding, Z, Wu, J & Dong, C 2021, 'Fibrinogen and fibrin differentially regulate the local hydrodynamic environment in neutrophil–tumor cell–endothelial cell adhesion system', Applied Sciences (Switzerland), vol. 11, no. 1, 79, pp. 1-14. https://doi.org/10.3390/app11010079

2020

Guo, J, Tian, X, Xie, D, Rahn, K, Gerhard, E, Kuzma, ML, Zhou, D, Dong, C, Bai, X, Lu, Z & Yang, J 2020, 'Citrate-Based Tannin-Bridged Bone Composites for Lumbar Fusion', Advanced Functional Materials, vol. 30, no. 27, 2002438. https://doi.org/10.1002/adfm.202002438
Kim, GB, Aragon-Sanabria, V, Randolph, L, Jiang, H, Reynolds, JA, Webb, BS, Madhankumar, A, Lian, X, Connor, JR, Yang, J & Dong, C 2020, 'High-affinity mutant Interleukin-13 targeted CAR T cells enhance delivery of clickable biodegradable fluorescent nanoparticles to glioblastoma', Bioactive Materials, vol. 5, no. 3, pp. 624-635. https://doi.org/10.1016/j.bioactmat.2020.04.011
Shi, P, Wang, X, Davis, B, Coyne, J, Dong, C, Reynolds, J & Wang, Y 2020, 'In Situ Synthesis of an Aptamer-Based Polyvalent Antibody Mimic on the Cell Surface for Enhanced Interactions between Immune and Cancer Cells', Angewandte Chemie - International Edition, vol. 59, no. 29, pp. 11892-11897. https://doi.org/10.1002/anie.202004206
Cochrane, KA, Zhang, T, Kozhakhmetov, A, Lee, JH, Zhang, F, Dong, C, Neaton, JB, Robinson, JA, Terrones, M, Bargioni, AW & Schuler, B 2020, 'Intentional carbon doping reveals CH as an abundant charged impurity in nominally undoped synthetic WS2 and WSe2 ', 2D Materials, vol. 7, no. 3, 031003. https://doi.org/10.1088/2053-1583/ab8543

2019

He, Y, Li, Q, Ma, C, Xie, D, Li, L, Zhao, Y, Shan, D, Chomos, SK, Dong, C, Tierney, JW, Sun, L, Lu, D, Gui, L & Yang, J 2019, 'Development of osteopromotive poly (octamethylene citrate glycerophosphate) for enhanced bone regeneration', Acta Biomaterialia, vol. 93, pp. 180-191. https://doi.org/10.1016/j.actbio.2019.03.050

2018

Ye, K, Kaplan, DL, Bao, G, Bettinger, C, Forgacs, G, Dong, C, Khademhosseini, A, Ke, Y, Leong, K, Sambanis, A, Sun, W & Yin, P 2018, 'Advanced Cell and Tissue Biomanufacturing', ACS Biomaterials Science and Engineering, vol. 4, no. 7, pp. 2292-2307. https://doi.org/10.1021/acsbiomaterials.8b00650
Aragon-Sanabria, V, Kim, GB & Dong, C 2018, From cancer immunoediting to new strategies in cancer immunotherapy: The roles of immune cells and mechanics in oncology. in Advances in Experimental Medicine and Biology. Advances in Experimental Medicine and Biology, vol. 1092, Springer New York LLC, pp. 113-138. https://doi.org/10.1007/978-3-319-95294-9_7
Sanabria, VA & Dong, C 2018, 'Integration of biochemical and biomechanical signals regulating endothelial barrier function', MCB Molecular and Cellular Biomechanics, vol. 15, no. 1, pp. 1-19. https://doi.org/10.3970/mcb.2018.015.001
Dong, C, Zahir, N & Konstantopoulos, K 2018, 'Preface', Advances in experimental medicine and biology, vol. 1092, pp. v-vi.
Kim, GB, Chen, Y, Kang, W, Guo, J, Payne, R, Li, H, Wei, Q, Baker, J, Dong, C, Zhang, S, Wong, PK, Rizk, EB, Yan, J & Yang, J 2018, 'The critical chemical and mechanical regulation of folic acid on neural engineering', Biomaterials, vol. 178, pp. 504-516. https://doi.org/10.1016/j.biomaterials.2018.03.059

2017

Tang, X, Loc, WS, Dong, C, Matters, GL, Butler, PJ, Kester, M, Meyers, C, Jiang, Y & Adair, JH 2017, 'The use of nanoparticulates to treat breast cancer', Nanomedicine, vol. 12, no. 19, pp. 2367-2388. https://doi.org/10.2217/nnm-2017-0202
Aragon-Sanabria, V, Pohler, SE, Eswar, VJ, Bierowski, M, Gomez, EW & Dong, C 2017, 'VE-Cadherin Disassembly and Cell Contractility in the Endothelium are Necessary for Barrier Disruption Induced by Tumor Cells', Scientific reports, vol. 7, 45835. https://doi.org/10.1038/srep45835

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)