Researcher Profile

Researcher Profile

Christopher Norbury, PhD

Christopher Norbury, PhD

Professor, Department of Microbiology and Immunology
Scientific Program:Mechanisms of Carcinogenesis
ccn1@psu.edu

Research Interests

  • T-Lymphocytes
  • Dendritic Cells
  • Antigens
  • Peptides
  • Cross-Priming
  • Virus Diseases
  • Viruses
  • Proteins
  • Vaccinia virus
  • Infections
  • Antigen Presentation
  • Immunity

Recent Publications

2021

Monticelli, SR, Bryk, P, Brewer, MG, Aguilar, HC, Norbury, CC & Ward, BM 2021, 'An increase in glycoprotein concentration on extracellular virions dramatically alters vaccinia virus infectivity and pathogenesis without impacting immunogenicity', PLoS pathogens, vol. 17, no. 12, e1010177. https://doi.org/10.1371/journal.ppat.1010177
Wu, X, Thylur, RP, Dayanand, KK, Punnath, K, Norbury, CC & Channe Gowda, D 2021, 'IL-4 treatment mitigates experimental cerebral malaria by reducing parasitemia, dampening inflammation, and lessening the cytotoxicity of T cells', Journal of Immunology, vol. 206, no. 1, pp. 118-131. https://doi.org/10.4049/jimmunol.2000779
Wu, X, Brombacher, F, Chroneos, ZC, Norbury, CC & Gowda, DC 2021, 'IL-4Rα signaling by CD8α+ dendritic cells contributes to cerebral malaria by enhancing inflammatory, Th1, and cytotoxic CD8+ T cell responses', Journal of Biological Chemistry, vol. 296, 100615. https://doi.org/10.1016/j.jbc.2021.100615

2020

Monticelli, SR, Earley, AK, Stone, R, Norbury, CC & Ward, BM 2020, 'Vaccinia Virus Glycoproteins A33, A34, and B5 Form a Complex for Efficient Endoplasmic Reticulum to trans-Golgi Network Transport', Journal of virology, vol. 94, no. 7, e0215519. https://doi.org/10.1128/JVI.02155-19

2019

Niu, TK, Princiotta, MF, Sei, JJ & Norbury, CC 2019, 'Analysis of MHC Class I Processing Pathways That Generate a Response to Vaccinia Virus Late Proteins', ImmunoHorizons, vol. 3, no. 12, pp. 559-572. https://doi.org/10.4049/immunohorizons.1900074
Parekh, NJ, Krouse, TE, Reider, IE, Hobbs, RP, Ward, BM & Norbury, CC 2019, 'Type I interferon-dependent CCL4 is induced by a cGAS/STING pathway that bypasses viral inhibition and protects infected tissue, independent of viral burden', PLoS pathogens, vol. 15, no. 10, e1007778. https://doi.org/10.1371/journal.ppat.1007778

Clinical Trials Search


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