Andrew Fraser Read, PhD - Penn State Cancer Institute
Researcher Profile
Andrew Fraser Read, PhD
Professor of Biotechnology, Eberly College of Science
Interim Senior Vice President for Research, Office of the Senior Vice President for Research
Evan Pugh Professor of Biology and Entomology, Eberly Professor of Biotechnology, Biology
Center for Infectious Disease Dynamics
Interim Senior Vice President for Research, Office of the Senior Vice President for Research
Evan Pugh Professor of Biology and Entomology, Eberly Professor of Biotechnology, Biology
Center for Infectious Disease Dynamics
Research Interests
- Malaria
- Parasites
- Infections
- Virulence
- Culicidae
- Rodentia
- Plasmodium chabaudi
- Pharmaceutical Preparations
- Clone Cells
- Population
- Drug Resistance
- Vaccines
Recent Publications
2023
Woods, RJ & Read, AF 2023, 'Combination antimicrobial therapy to manage resistance', Evolution, Medicine and Public Health, vol. 11, no. 1, pp. 185-186. https://doi.org/10.1093/emph/eoad005
Woods, RJ, Barbosa, C, Koepping, L, Raygoza, JA, Mwangi, M & Read, AF 2023, 'The evolution of antibiotic resistance in an incurable and ultimately fatal infection: A retrospective case study', Evolution, Medicine and Public Health, vol. 11, no. 1, pp. 163-173. https://doi.org/10.1093/emph/eoad012
2022
Arnold, CRK, Srinivasan, S, Rodriguez, S, Rydzak, N, Herzog, CM, Gontu, A, Bharti, N, Small, M, Rogers, CJ, Schade, MM, Kuchipudi, SV, Kapur, V, Read, AF & Ferrari, MJ 2022, 'A longitudinal study of the impact of university student return to campus on the SARS-CoV-2 seroprevalence among the community members', Scientific reports, vol. 12, no. 1, 8586. https://doi.org/10.1038/s41598-022-12499-5
Morley, VJ, Sim, DG, Penkevich, A, Woods, RJ & Read, AF 2022, 'An orally administered drug prevents selection for antibiotic-resistant bacteria in the gut during daptomycin therapy', Evolution, Medicine and Public Health, vol. 10, no. 1, pp. 439-446. https://doi.org/10.1093/emph/eoac035
Kerr, PJ, Cattadori, IM, Sim, D, Liu, J, Holmes, EC & Read, AF 2022, 'Divergent Evolutionary Pathways of Myxoma Virus in Australia: Virulence Phenotypes in Susceptible and Partially Resistant Rabbits Indicate Possible Selection for Transmissibility', Journal of virology, vol. 96, no. 20. https://doi.org/10.1128/jvi.00886-22
Hayden, KR, Jones, M, Elkin, KR, Shreve, MJ, Clees, WI, Clark, S, Mashtare, ML, Veith, TL, Elliott, HA, Watson, JE, Silverman, J, Richard, TL, Read, AF & Preisendanz, HE 2022, 'Impacts of the COVID-19 pandemic on pharmaceuticals in wastewater treated for beneficial reuse: Two case studies in central Pennsylvania', Journal of Environmental Quality, vol. 51, no. 5, pp. 1066-1082. https://doi.org/10.1002/jeq2.20398
Yeh, SL, Narasimhalu, N, Vom Steeg, LG, Muthami, J, Leconey, S, He, Z, Pitcher, M, Cassady, H, Morley, VJ, Cho, SH, Bator, C, Koshani, R, Woods, RJ, Hickner, M, Read, AF & Sheikhi, A 2022, 'Ion Exchange Biomaterials to Capture Daptomycin and Prevent Resistance Evolution in Off-Target Bacterial Populations', ACS Applied Materials and Interfaces, vol. 14, no. 38, pp. 42864-42875. https://doi.org/10.1021/acsami.2c14894
Day, T, Kennedy, DA, Read, AF & Gandon, S 2022, 'Pathogen evolution during vaccination campaigns', PLoS biology, vol. 20, no. 9, pp. e3001804. https://doi.org/10.1371/journal.pbio.3001804
2021
Day, T, Kennedy, DA, Read, AF & McAdams, D 2021, 'The economics of managing evolution', PLoS biology, vol. 19, no. 11, e3001409. https://doi.org/10.1371/journal.pbio.3001409
2020
Morley, VJ, Kinnear, CL, Sim, DG, Olson, SN, Jackson, LM, Hansen, E, Usher, GA, Showalter, SA, Pai, MP, Woods, RJ & Read, AF 2020, 'An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen', eLife, vol. 9, e58147, pp. 1-17. https://doi.org/10.7554/eLife.58147
Hansen, E, Karslake, J, Woods, RJ, Read, AF & Wood, KB 2020, 'Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations', PLoS biology, vol. 18, no. 5, e3000713. https://doi.org/10.1371/journal.pbio.3000713
Hansen, E & Read, AF 2020, 'Cancer therapy: Attempt cure or manage drug resistance?', Evolutionary Applications, vol. 13, no. 7, pp. 1660-1672. https://doi.org/10.1111/eva.12994
Kinnear, CL, Hansen, E, Morley, VJ, Tracy, KC, Forstchen, M, Read, AF & Woods, RJ 2020, 'Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium', PLoS biology, vol. 18, no. 12, pp. e3000987. https://doi.org/10.1371/journal.pbio.3000987
Acosta, MM, Bram, JT, Sim, D & Read, AF 2020, 'Effect of drug dose and timing of treatment on the emergence of drug resistance in vivo in a malaria model', Evolution, Medicine and Public Health, vol. 2020, no. 1, pp. 196-210. https://doi.org/10.1093/EMPH/EOAA016
Greischar, MA, Alexander, HK, Bashey, F, Bento, AI, Bhattacharya, A, Bushman, M, Childs, LM, Daversa, DR, Day, T, Faust, CL, Gallagher, ME, Gandon, S, Glidden, CK, Halliday, FW, Hanley, KA, Kamiya, T, Read, AF, Schwabl, P, Sweeny, AR, Tate, AT, Thompson, RN, Wale, N, Wearing, HJ, Yeh, PJ & Mideo, N 2020, 'Evolutionary consequences of feedbacks between within-host competition and disease control', Evolution, Medicine and Public Health, vol. 2020, no. 1, pp. 30-34. https://doi.org/10.1093/emph/eoaa004
Morley, VJ, Firgens, EPC, Vanderbilt, RR, Zhou, Y, Zook, M, Read, AF & MacGeorge, EL 2020, 'Factors associated with antibiotic prescribing for acute bronchitis at a university health center', BMC Infectious Diseases, vol. 20, no. 1, 177. https://doi.org/10.1186/s12879-020-4825-2
Dujon, AM, Aktipis, A, Alix-Panabières, C, Amend, SR, Boddy, AM, Brown, JS, Capp, JP, DeGregori, J, Ewald, P, Gatenby, R, Gerlinger, M, Giraudeau, M, Hamede, RK, Hansen, E, Kareva, I, Maley, CC, Marusyk, A, McGranahan, N, Metzger, MJ, Nedelcu, AM, Noble, R, Nunney, L, Pienta, KJ, Polyak, K, Pujol, P, Read, AF, Roche, B, Sebens, S, Solary, E, Staňková, K, Swain Ewald, H, Thomas, F & Ujvari, B 2020, 'Identifying key questions in the ecology and evolution of cancer', Evolutionary Applications, vol. 14, no. 4, pp. 877-892. https://doi.org/10.1111/eva.13190
Hansen, E & Read, AF 2020, 'Modifying adaptive therapy to enhance competitive suppression', Cancers, vol. 12, no. 12, 3556, pp. 1-13. https://doi.org/10.3390/cancers12123556
Kennedy, DA, Read, AF & Kennedy, DA 2020, 'Monitor for COVID-19 vaccine resistance evolution during clinical trials', PLoS biology, vol. 18, no. 11, e3001000. https://doi.org/10.1371/journal.pbio.3001000
Sutcliffe, J, McLaughlin, R, Webster, G, Read, AF, Drlica, K, Elliott, R & Stuart, I 2020, 'Susceptibility of Cutibacterium acnes to topical minocycline foam', Anaerobe, vol. 62, 102169. https://doi.org/10.1016/j.anaerobe.2020.102169