Aron Lukacher, MD, PhD - Penn State Cancer Institute
Researcher Profile
Aron Lukacher, MD, PhD
Professor, Department of Cell and Biological Systems
Professor, Department of Pathology and Laboratory Medicine
One Health Microbiome Center
Professor, Department of Pathology and Laboratory Medicine
One Health Microbiome Center
Scientific Program:Mechanisms of Carcinogenesis
Recent Publications
2024
Butic, AB, Katz, ZE, Jin, G, Fukushima, K, Hazama, M, Lukacher, AE & Lauver, MD 2024, 'Brincidofovir inhibits polyomavirus infection in vivo', mBio, vol. 15, no. 8. https://doi.org/10.1128/mbio.01049-24
2023
Pham, AM, Ortiz, LE, Lukacher, AE & Kwun, HJ 2023, 'Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain', Cells, vol. 12, no. 3, 380. https://doi.org/10.3390/cells12030380
Butic, AB, Spencer, SA, Shaheen, SK & Lukacher, AE 2023, 'Polyomavirus Wakes Up and Chooses Neurovirulence', Viruses, vol. 15, no. 10, 2112. https://doi.org/10.3390/v15102112
2022
Lauver, MD, Jin, G, Ayers, KN, Carey, SN, Specht, CS, Abendroth, CS & Lukacher, AE 2022, 'T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus', eLife, vol. 11, e83030. https://doi.org/10.7554/ELIFE.83030
2021
Netherby-Winslow, CS, Ayers, KN & Lukacher, AE 2021, 'Balancing Inflammation and Central Nervous System Homeostasis: T Cell Receptor Signaling in Antiviral Brain TRM Formation and Function', Frontiers in immunology, vol. 11, 624144. https://doi.org/10.3389/fimmu.2020.624144
Ren, HM, Lukacher, AE, Rahman, ZSM & Olsen, NJ 2021, 'New developments implicating IL-21 in autoimmune disease', Journal of Autoimmunity, vol. 122, 102689. https://doi.org/10.1016/j.jaut.2021.102689
Ayers, KN, Carey, SN & Lukacher, AE 2022, 'Understanding polyomavirus CNS disease – a perspective from mouse models', FEBS Journal, vol. 289, no. 19, pp. 5744-5761. https://doi.org/10.1111/febs.16083