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Researcher Profile

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Andrew David Patterson, PhD

Andrew David Patterson, PhD

Biochemistry & Molecular Biology
Professor, Veterinary and Biomedical Sciences
Scientific Program:Mechanisms of Carcinogenesis

Research Interests

  • Metabolomics
  • Gastrointestinal Microbiome
  • Microbiota
  • Liver
  • Diet
  • Bile Acids and Salts
  • Aryl Hydrocarbon Receptors
  • Mass Spectrometry
  • Neoplasms
  • Homeostasis
  • Serum
  • Genes

Recent Publications


Zhu, X, Liu, Q, Patterson, AD, Sharma, AK, Amin, SG, Cohen, SM, Gonzalez, FJ & Peters, JM 2023, 'Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in Ppara Transgenic Mice', Metabolites, vol. 13, no. 8, 936.
Zhou, X, Chakraborty, D, Murray, IA, Coslo, D, Kehs, Z, Vijay, A, Ton, C, Desai, D, Amin, SG, Patterson, AD & Perdew, GH 2023, 'Aryl Hydrocarbon Receptor Activation Coordinates Mouse Small Intestinal Epithelial Cell Programming', Laboratory Investigation, vol. 103, no. 2, pp. 100012.
Vijay, A, Boyle, NR, Kumar, SM, Perdew, GH, Srinivasan, S & Patterson, AD 2023, 'Aryl hydrocarbon receptor activation affects nitrergic neuronal survival and delays intestinal motility in mice', Toxicological Sciences, vol. 192, no. 1, pp. 117-128.
Sun, L, Zhang, Y, Cai, J, Rimal, B, Rocha, ER, Coleman, JP, Zhang, C, Nichols, RG, Luo, Y, Kim, B, Chen, Y, Krausz, KW, Harris, CC, Patterson, AD, Zhang, Z, Takahashi, S & Gonzalez, FJ 2023, 'Bile salt hydrolase in non-enterotoxigenic Bacteroides potentiates colorectal cancer', Nature communications, vol. 14, no. 1, 755.
Bass, R, Tanes, C, Bittinger, K, Li, Y, Lee, H, Friedman, ES, Koo, I, Patterson, AD, Liu, Q, Wu, GD & Stallings, VA 2023, 'Changes in fecal lipidome after treatment with ivacaftor without changes in microbiome or bile acids', Journal of Cystic Fibrosis.
Hwang, S, Koo, I, Patterson, AD & Lambert, JD 2023, 'Comparative urine metabolomics of mice treated with non-toxic and toxic oral doses of (−)-epigallocatechin-3-gallate', Food and Function, vol. 14, no. 20, pp. 9434-9445.
Dong, F, Murray, IA, Annalora, A, Coslo, DM, Desai, D, Gowda, K, Yang, J, Wang, D, Koo, I, Hao, F, Amin, SG, Patterson, AD, Marcus, C & Perdew, GH 2023, 'Complex chemical signals dictate Ah receptor activation through the gut-lung axis', FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol. 37, no. 7, pp. e23010.
Morgan, EW, Dong, F, Annalora, AJ, Murray, IA, Wolfe, T, Erickson, R, Gowda, K, Amin, SG, Petersen, KS, Kris-Etherton, PM, Marcus, CB, Walk, ST, Patterson, AD & Perdew, GH 2023, 'Contribution of Circulating Host and Microbial Tryptophan Metabolites Toward Ah Receptor Activation', International Journal of Tryptophan Research, vol. 16.
Dong, F, Annalora, AJ, Murray, IA, Tian, Y, Marcus, CB, Patterson, AD & Perdew, GH 2023, 'Endogenous Tryptophan-Derived Ah Receptor Ligands are Dissociated from CYP1A1/1B1-Dependent Negative-Feedback', International Journal of Tryptophan Research, vol. 16.
Young, JA, Duran-Ortiz, S, Bell, S, Funk, K, Tian, Y, Liu, Q, Patterson, AD, List, EO, Berryman, DE & Kopchick, JJ 2023, 'Growth Hormone Alters Circulating Levels of Glycine and Hydroxyproline in Mice', Metabolites, vol. 13, no. 2, 191.
Patel, D, Murray, IA, Dong, F, Annalora, AJ, Gowda, K, Coslo, DM, Krzeminski, J, Koo, I, Hao, F, Amin, SG, Marcus, CB, Patterson, AD & Perdew, GH 2023, 'Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites', Metabolites, vol. 13, no. 9, 985.
Misra, S, Lee, TJ, Sebastian, A, McGuigan, J, Liao, C, Koo, I, Patterson, AD, Rossi, RM, Hall, MA, Albert, I & Prabhu, KS 2023, 'Loss of selenoprotein W in murine macrophages alters the hierarchy of selenoprotein expression, redox tone, and mitochondrial functions during inflammation', Redox Biology, vol. 59, 102571.
Chen, X, Patterson, AD, Perdew, GH, Murray, IA & Kellogg, JJ 2023, 'Molecular networking identifies an AHR-modulating benzothiazole from white button mushrooms (Agaricus bisporus)', Journal of Functional Foods, vol. 106, 105602.
Shalon, D, Culver, RN, Grembi, JA, Folz, J, Treit, PV, Shi, H, Rosenberger, FA, Dethlefsen, L, Meng, X, Yaffe, E, Aranda-Díaz, A, Geyer, PE, Mueller-Reif, JB, Spencer, S, Patterson, AD, Triadafilopoulos, G, Holmes, SP, Mann, M, Fiehn, O, Relman, DA & Huang, KC 2023, 'Profiling the human intestinal environment under physiological conditions', Nature, vol. 617, no. 7961, pp. 581-591.
Bretin, A, Zou, J, San Yeoh, B, Ngo, VL, Winer, S, Winer, DA, Reddivari, L, Pellizzon, M, Walters, WA, Patterson, AD, Ley, R, Chassaing, B, Vijay-Kumar, M & Gewirtz, AT 2023, 'Psyllium Fiber Protects Against Colitis Via Activation of Bile Acid Sensor Farnesoid X Receptor', CMGH, vol. 15, no. 6, pp. 1421-1442.
Tian, S, Paudel, D, Hao, F, Neupane, R, Castro, R, Patterson, AD, Tiwari, AK, Prabhu, KS & Singh, V 2023, 'Refined fiber inulin promotes inflammation-associated colon tumorigenesis by modulating microbial succinate production', Cancer Reports, vol. 6, no. 11, e1863.
Perdew, GH, Esser, C, Snyder, M, Sherr, DH, van den Bogaard, EH, McGovern, K, Fernández-Salguero, PM, Coumoul, X & Patterson, AD 2023, 'The Ah Receptor from Toxicity to Therapeutics: Report from the 5th AHR Meeting at Penn State University, USA, June 2022', International journal of molecular sciences, vol. 24, no. 6, 5550.
Yeoh, BS, Golonka, RM, Saha, P, Kandalgaonkar, MR, Tian, Y, Osman, I, Patterson, AD, Gewirtz, AT, Joe, B & Vijay-Kumar, M 2023, 'Urine-based Detection of Congenital Portosystemic Shunt in C57BL/6 Mice', Function, vol. 4, no. 5, zqad040.


Dohnalová, L, Lundgren, P, Carty, JRE, Goldstein, N, Wenski, SL, Nanudorn, P, Thiengmag, S, Huang, KP, Litichevskiy, L, Descamps, HC, Chellappa, K, Glassman, A, Kessler, S, Kim, J, Cox, TO, Dmitrieva-Posocco, O, Wong, AC, Allman, EL, Ghosh, S, Sharma, N, Sengupta, K, Cornes, B, Dean, N, Churchill, GA, Khurana, TS, Sellmyer, MA, FitzGerald, GA, Patterson, AD, Baur, JA, Alhadeff, AL, Helfrich, EJN, Levy, M, Betley, JN & Thaiss, CA 2022, 'A microbiome-dependent gut–brain pathway regulates motivation for exercise', Nature, vol. 612, no. 7941, pp. 739-747.
Granados, JC, Falah, K, Koo, I, Morgan, EW, Perdew, GH, Patterson, AD, Jamshidi, N & Nigam, SK 2022, 'AHR is a master regulator of diverse pathways in endogenous metabolism', Scientific reports, vol. 12, no. 1, 16625.
Alrehaili, BD, Lee, M, Takahashi, S, Novak, R, Rimal, B, Boehme, S, Trammell, SAJ, Grevengoed, TJ, Kumar, D, Alnouti, Y, Chiti, K, Wang, X, Patterson, AD, Chiang, JYL, Gonzalez, FJ & Lee, YK 2022, 'Bile acid conjugation deficiency causes hypercholanemia, hyperphagia, islet dysfunction, and gut dysbiosis in mice', Hepatology Communications, vol. 6, no. 10, pp. 2765-2780.
Cai, J, Rimal, B, Jiang, C, Chiang, JYL & Patterson, AD 2022, 'Bile acid metabolism and signaling, the microbiota, and metabolic disease', Pharmacology and Therapeutics, vol. 237, 108238.
Collins, SL, Stine, JG, Bisanz, JE, Okafor, CD & Patterson, AD 2023, 'Bile acids and the gut microbiota: metabolic interactions and impacts on disease', Nature Reviews Microbiology, vol. 21, no. 4, pp. 236-247.
Mohammed, AD, Mohammed, Z, Roland, MM, Chatzistamou, I, Jolly, A, Schoettmer, LM, Arroyo, M, Kakar, K, Tian, Y, Patterson, A, Nagarkatti, M, Nagarkatti, P & Kubinak, JL 2022, 'Defective humoral immunity disrupts bile acid homeostasis which promotes inflammatory disease of the small bowel', Nature communications, vol. 13, no. 1, 525.
Delaroque, C, Wu, GD, Compher, C, Ni, J, Albenberg, L, Liu, Q, Tian, Y, Patterson, AD, Lewis, JD, Gewirtz, AT & Chassaing, B 2022, 'Diet standardization reduces intra-individual microbiome variation', Gut microbes, vol. 14, no. 1, pp. 2149047.
Tian, Y, Rimal, B, Gui, W, Koo, I, Smith, PB, Yokoyama, S & Patterson, AD 2022, 'Early Life Polychlorinated Biphenyl 126 Exposure Disrupts Gut Microbiota and Metabolic Homeostasis in Mice Fed with High-Fat Diet in Adulthood', Metabolites, vol. 12, no. 10, 894.
Tian, Y, Rimal, B, Gui, W, Koo, I, Yokoyama, S, Perdew, GH & Patterson, AD 2022, 'Early Life Short-Term Exposure to Polychlorinated Biphenyl 126 in Mice Leads to Metabolic Dysfunction and Microbiota Changes in Adulthood', International journal of molecular sciences, vol. 23, no. 15, 8220.
Baldin, M, Garcia, D, Zanton, GI, Hao, F, Patterson, AD & Harvatine, KJ 2022, 'Effect of 2-hydroxy-4-(methylthio)butanoate (HMTBa) on milk fat, rumen environment and biohydrogenation, and rumen protozoa in lactating cows fed diets with increased risk for milk fat depression', Journal of dairy science, vol. 105, no. 9, pp. 7446-7461.
Seemiller, LR, Goldberg, LR, Smith, PB, Dennis, J, Patterson, AD & Gould, TJ 2022, 'Genetic differences in nicotine sensitivity and metabolism in C57BL/6J and NOD/ShiLtJ mouse strains', Neuropharmacology, vol. 221, 109279.
Jiang, J, Ma, Y, Liu, Y, Lu, D, Gao, X, Krausz, KW, Desai, D, Amin, SG, Patterson, AD, Gonzalez, FJ & Xie, C 2022, 'Glycine-β-muricholic acid antagonizes the intestinal farnesoid X receptor–ceramide axis and ameliorates NASH in mice', Hepatology Communications, vol. 6, no. 12, pp. 3363-3378.
Matamoros, C, Hao, F, Tian, Y, Patterson, AD & Harvatine, KJ 2022, 'Interaction of sodium acetate supplementation and dietary fiber level on feeding behavior, digestibility, milk synthesis, and plasma metabolites', Journal of dairy science, vol. 105, no. 11, pp. 8824-8838.
Morgan, EW, Perdew, GH & Patterson, AD 2022, 'Multi-Omics Strategies for Investigating the Microbiome in Toxicology Research', Toxicological Sciences, vol. 187, no. 2, pp. 189-213.
Chassaing, B, Compher, C, Bonhomme, B, Liu, Q, Tian, Y, Walters, W, Nessel, L, Delaroque, C, Hao, F, Gershuni, V, Chau, L, Ni, J, Bewtra, M, Albenberg, L, Bretin, A, McKeever, L, Ley, RE, Patterson, AD, Wu, GD, Gewirtz, AT & Lewis, JD 2022, 'Randomized Controlled-Feeding Study of Dietary Emulsifier Carboxymethylcellulose Reveals Detrimental Impacts on the Gut Microbiota and Metabolome', Gastroenterology, vol. 162, no. 3, pp. 743-756.
Su, S, Billy, LJ, Chang, S, Gonzalez, FJ, Patterson, AD & Peters, JM 2022, 'The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice', Toxicology, vol. 465, 153056.
Chalmers, FE, Mogre, S, Rimal, B, Son, J, Patterson, AD, Stairs, DB & Glick, AB 2022, 'The unfolded protein response gene Ire1α is required for tissue renewal and normal differentiation in the mouse tongue and esophagus', Developmental biology, vol. 492, pp. 59-70.


von Schwartzenberg, RJ, Bisanz, JE, Lyalina, S, Spanogiannopoulos, P, Ang, QY, Cai, J, Dickmann, S, Friedrich, M, Liu, SY, Collins, SL, Ingebrigtsen, D, Miller, S, Turnbaugh, JA, Patterson, AD, Pollard, KS, Mai, K, Spranger, J & Turnbaugh, PJ 2021, 'Caloric restriction disrupts the microbiota and colonization resistance', Nature, vol. 595, no. 7866, pp. 272-277.
Matamoros, C, Cai, J, Patterson, AD & Harvatine, KJ 2021, 'Comparison of the effects of short-term feeding of sodium acetate and sodium bicarbonate on milk fat production', Journal of dairy science, vol. 104, no. 7, pp. 7572-7582.
Collins, SL, Koo, I, Peters, JM, Smith, PB & Patterson, AD 2021, 'Current Challenges and Recent Developments in Mass Spectrometry-Based Metabolomics', Annual Review of Analytical Chemistry, vol. 14, pp. 467-487.
Hughes, A, Dahmus, J, Rivas, G, Hummer, B, Chen See, JR, Wright, JR, Lamendella, R, Schmitz, KH, Sciamanna, C, Ruffin, M, Patterson, AD, Loomba, R & Stine, JG 2021, 'Exercise Training Reverses Gut Dysbiosis in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis: A Proof of Concept Study', Clinical Gastroenterology and Hepatology, vol. 19, no. 8, pp. 1723-1725.
Shi, Z, Lei, H, Chen, G, Yuan, P, Cao, Z, Ser, HL, Zhu, X, Wu, F, Liu, C, Dong, M, Song, Y, Guo, Y, Chen, C, Hu, K, Zhu, Y, Zeng, XA, Zhou, J, Lu, Y, Patterson, AD & Zhang, L 2021, 'Impaired intestinal akkermansia muciniphila and aryl hydrocarbon receptor ligands contribute to nonalcoholic fatty liver disease in mice', mSystems, vol. 6, no. 1, e00985-20.
Nandy, D, Craig, SJC, Cai, J, Tian, Y, Paul, IM, Savage, JS, Marini, ME, Hohman, EE, Reimherr, ML, Patterson, AD, Makova, KD & Chiaromonte, F 2022, 'Metabolomic profiling of stool of two-year old children from the INSIGHT study reveals links between butyrate and child weight outcomes', Pediatric Obesity, vol. 17, no. 1, e12833.
Nayak, RR, Alexander, M, Deshpande, I, Stapleton-Gray, K, Rimal, B, Patterson, AD, Ubeda, C, Scher, JU & Turnbaugh, PJ 2021, 'Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation', Cell Host and Microbe, vol. 29, no. 3, pp. 362-377.e11.
Tian, Y, Cai, J, Allman, EL, Smith, PB & Patterson, AD 2021, Quantitative analysis of bile acid with UHPLC-MS/MS. in Methods in Molecular Biology. Methods in Molecular Biology, vol. 2194, Humana Press Inc., pp. 291-300.
Czernik, PJ, Golonka, RM, Chakraborty, S, Yeoh, BS, Abokor, AA, Saha, P, Yeo, JY, Mell, B, Cheng, X, Baroi, S, Tian, Y, Patterson, AD, Joe, B, Vijay-Kumar, M & Lecka-Czernik, B 2021, 'Reconstitution of the host holobiont in germ-free born male rats acutely increases bone growth and affects marrow cellular content', Physiological genomics, vol. 53, no. 12, pp. 518-533.
Rimal, B & Patterson, AD 2021, 'Role of bile acids and gut bacteria in healthy ageing of centenarians', Nature, vol. 599, no. 7885, pp. 380-381.
Mal, TK, Tian, Y & Patterson, AD 2021, Sample preparation and data analysis for NMR-based metabolomics. in Methods in Molecular Biology. Methods in Molecular Biology, vol. 2194, Humana Press Inc., pp. 301-313.
Winston, JA, Rivera, A, Cai, J, Patterson, AD & Theriot, CM 2021, 'Secondary bile acid ursodeoxycholic acid alters weight, the gut microbiota, and the bile acid pool in conventional mice', PloS one, vol. 16, no. 2 Febuary, e0246161.
Korwar, AM, Hossain, A, Lee, TJ, Shay, AE, Basrur, V, Conlon, K, Smith, PB, Carlson, BA, Salis, HM, Patterson, AD & Prabhu, KS 2021, 'Selenium-dependent metabolic reprogramming during inflammation and resolution', Journal of Biological Chemistry, vol. 296, 100410.
Liu, Q, Zhang, L, Allman, EL, Hubbard, TD, Murray, IA, Hao, F, Tian, Y, Gui, W, Nichols, RG, Smith, PB, Anitha, M, Perdew, GH & Patterson, AD 2021, 'The aryl hydrocarbon receptor activates ceramide biosynthesis in mice contributing to hepatic lipogenesis', Toxicology, vol. 458, 152831.
Ang, QY, Alba, DL, Upadhyay, V, Bisanz, JE, Cai, J, Lee, HL, Barajas, E, Wei, G, Noecker, C, Patterson, AD, Koliwad, SK & Turnbaugh, PJ 2021, 'The east asian gut microbiome is distinct from colocalized white subjects and connected to metabolic health', eLife, vol. 10, e70349.


Man, K, Bowman, C, Braverman, KN, Escalante, V, Tian, Y, Bisanz, JE, Ganeshan, K, Wang, B, Patterson, A, Bayrer, JR, Turnbaugh, PJ & Chawla, A 2020, 'A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 50, pp. 32029-32037.
Bittinger, K, Zhao, C, Li, Y, Ford, E, Friedman, ES, Ni, J, Kulkarni, CV, Cai, J, Tian, Y, Liu, Q, Patterson, AD, Sarkar, D, Chan, SHJ, Maranas, C, Saha-Shah, A, Lund, P, Garcia, BA, Mattei, LM, Gerber, JS, Elovitz, MA, Kelly, A, DeRusso, P, Kim, D, Hofstaedter, CE, Goulian, M, Li, H, Bushman, FD, Zemel, BS & Wu, GD 2020, 'Bacterial colonization reprograms the neonatal gut metabolome', Nature Microbiology, vol. 5, no. 6, pp. 838-847.
McMullen, JG, Peters-Schulze, G, Cai, J, Patterson, AD & Douglas, AE 2020, 'How gut microbiome interactions affect nutritional traits of Drosophila melanogaster', Journal of Experimental Biology, vol. 223, no. 19, jeb227843.
Blow, F, Ankrah, NYD, Clark, N, Koo, I, Allman, EL, Liu, Q, Anitha, M, Patterson, AD & Douglas, AE 2020, 'Impact of facultative bacteria on the metabolic function of an obligate insect-bacterial symbiosis', mBio, vol. 11, no. 4, e00402-20, pp. 1-12.
Dong, F, Hao, F, Murray, IA, Smith, PB, Koo, I, Tindall, AM, Kris-Etherton, PM, Gowda, K, Amin, SG, Patterson, AD & Perdew, GH 2020, 'Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity', Gut microbes, vol. 12, no. 1, pp. 1-24.
Ang, QY, Alexander, M, Newman, JC, Tian, Y, Cai, J, Upadhyay, V, Turnbaugh, JA, Verdin, E, Hall, KD, Leibel, RL, Ravussin, E, Rosenbaum, M, Patterson, AD & Turnbaugh, PJ 2020, 'Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells', Cell, vol. 181, no. 6, pp. 1263-1275.e16.
Singh, V, Galla, S, Golonka, RM, Patterson, AD, Chassaing, B, Joe, B & Vijay-Kumar, M 2020, 'Lipocalin 2 deficiency-induced gut microbiota dysbiosis evokes metabolic syndrome in aged mice', Physiological genomics, vol. 52, no. 8, pp. 314-321.
Patt, A, Demoret, B, Stets, C, Bill, KL, Smith, P, Vijay, A, Patterson, A, Hays, J, Hoang, M, Chen, JL & Mathé, EA 2020, 'Mdm2-dependent rewiring of metabolomic and lipidomic profiles in dedifferentiated liposarcoma models', Cancers, vol. 12, no. 8, 2157, pp. 1-14.
Tian, Y, Gui, W, Rimal, B, Koo, I, Smith, PB, Nichols, RG, Cai, J, Liu, Q & Patterson, AD 2020, 'Metabolic impact of persistent organic pollutants on gut microbiota', Gut microbes, vol. 12, no. 1, pp. 1-16.
Allen, JN, Dey, A, Cai, J, Zhang, J, Tian, Y, Kennett, M, Ma, Y, Liang, TJ, Patterson, AD & Hankey-Giblin, PA 2020, 'Metabolic profiling reveals aggravated non-alcoholic steatohepatitis in high-fat high-cholesterol diet-fed apolipoprotein e-deficient mice lacking ron receptor signaling', Metabolites, vol. 10, no. 8, 326, pp. 1-24.
Nichols, RG, Zhang, J, Cai, J, Murray, IA, Koo, I, Smith, PB, Perdew, GH & Patterson, AD 2020, 'Metatranscriptomic analysis of the mouse gut microbiome response to the persistent organic pollutant 2,3,7,8-tetrachlorodibenzofuran', Metabolites, vol. 10, no. 1, 1.
Das, NK, Schwartz, AJ, Barthel, G, Inohara, N, Liu, Q, Sankar, A, Hill, DR, Ma, X, Lamberg, O, Schnizlein, MK, Arqués, JL, Spence, JR, Nunez, G, Patterson, AD, Sun, D, Young, VB & Shah, YM 2020, 'Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis', Cell Metabolism, vol. 31, no. 1, pp. 115-130.e6.
Stine, JG, Schreibman, I, Navabi, S, Kang, M, Dahmus, J, Soriano, C, Rivas, G, Hummer, B, Beyer, M, Tressler, H, Kimball, SR, Patterson, AD, Schmitz, K & Sciamanna, C 2020, 'Nonalcoholic steatohepatitis Fitness Intervention in Thrombosis (NASHFit): Study protocol for a randomized controlled trial of a supervised aerobic exercise program to reduce elevated clotting risk in patients with NASH', Contemporary Clinical Trials Communications, vol. 18, 100560.
Zhang, L, Rimal, B, Nichols, RG, Tian, Y, Smith, PB, Hatzakis, E, Chang, SC, Butenhoff, JL, Peters, JM & Patterson, AD 2020, 'Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice', Toxicology, vol. 431, 152365.
Noel, OF, Chu, X, Patterson, AD, Edwards, MA, Still, CD & Gerhard, GS 2021, 'Roux-en-Y Gastric Bypass Surgery Has Early Differential Effects on Bile Acids and the Levels of Complement Component 3 and Acylation-Stimulating Protein', Obesity Surgery, vol. 31, no. 2, pp. 773-780.
Artacho, A, Isaac, S, Nayak, R, Flor-Duro, A, Alexander, M, Koo, I, Manasson, J, Smith, PB, Rosenthal, P, Homsi, Y, Gulko, P, Pons, J, Puchades-Carrasco, L, Izmirly, P, Patterson, A, Abramson, SB, Pineda-Lucena, A, Turnbaugh, PJ, Ubeda, C & Scher, JU 2021, 'The Pretreatment Gut Microbiome Is Associated With Lack of Response to Methotrexate in New-Onset Rheumatoid Arthritis', Arthritis and Rheumatology, vol. 73, no. 6, pp. 931-942.
Collins, SL & Patterson, AD 2020, 'The gut microbiome: an orchestrator of xenobiotic metabolism', Acta Pharmaceutica Sinica B, vol. 10, no. 1, pp. 19-32.
Tian, Y, Gui, W, Koo, I, Smith, PB, Allman, EL, Nichols, RG, Rimal, B, Cai, J, Liu, Q & Patterson, AD 2020, 'The microbiome modulating activity of bile acids', Gut microbes, vol. 11, no. 4, pp. 979-996.
Winston, JA, Rivera, AJ, Cai, J, Thanissery, R, Montgomery, SA, Patterson, AD & Theriot, CM 2020, 'Ursodeoxycholic acid (udca) mitigates the host inflammatory response during clostridioides difficile infection by altering gut bile acids', Infection and Immunity, vol. 88, no. 6, e00045.
Singh, V, Yeoh, BS, Abokor, AA, Golonka, RM, Tian, Y, Patterson, AD, Joe, B, Heikenwalder, M & Vijay-Kumar, M 2020, 'Vancomycin prevents fermentable fiber-induced liver cancer in mice with dysbiotic gut microbiota', Gut microbes, vol. 11, no. 4, pp. 1077-1091.


Dutta, M, Cai, J, Gui, W & Patterson, AD 2019, 'A review of analytical platforms for accurate bile acid measurement', Analytical and Bioanalytical Chemistry, vol. 411, no. 19, pp. 4541-4549.
Tian, Y, Cai, J, Gui, W, Nichols, RG, Koo, I, Zhang, J, Anitha, M & Patterson, AD 2019, 'Berberine directly affects the gut microbiota to promote intestinal farnesoid X receptor activation', Drug Metabolism and Disposition, vol. 47, no. 2, pp. 86-93.
Zheng, X, Smith, FB, Aly, NA, Cai, J, Smith, RD, Patterson, AD & Baker, ES 2019, 'Evaluating the structural complexity of isomeric bile acids with ion mobility spectrometry', Analytical and Bioanalytical Chemistry, vol. 411, no. 19, pp. 4673-4682.
Hao, S, Xiang, J, Wu, DC, Fraser, JW, Ruan, B, Cai, J, Patterson, AD, Lai, ZC & Paulson, RF 2019, 'Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche', Blood Advances, vol. 3, no. 14, pp. 2205-2217.
Alwerdt, J, Patterson, AD & Sliwinski, MJ 2019, 'Gender differences in phytoestrogens and the relationship with speed of processing in older adults: A cross-sectional analysis of NHANES, 1999–2002', Nutrients, vol. 11, no. 8, 1780.
Qi, X, Yun, C, Sun, L, Xia, J, Wu, Q, Wang, Y, Wang, L, Zhang, Y, Liang, X, Wang, L, Gonzalez, FJ, Patterson, AD, Liu, H, Mu, L, Zhou, Z, Zhao, Y, Li, R, Liu, P, Zhong, C, Pang, Y, Jiang, C & Qiao, J 2019, 'Gut microbiota–bile acid–interleukin-22 axis orchestrates polycystic ovary syndrome', Nature Medicine, vol. 25, no. 8, pp. 1225-1233.
Nichols, RG, Peters, JM & Patterson, AD 2019, 'Interplay Between the Host, the Human Microbiome, and Drug Metabolism', Human genomics, vol. 13, no. 1.
Tian, Y, Gui, W, Smith, PB, Koo, I, Murray, IA, Cantorna, MT, Perdew, GH & Patterson, AD 2019, 'Isolation and Identification of Aryl Hydrocarbon Receptor Modulators in White Button Mushrooms (Agaricus bisporus)', Journal of agricultural and food chemistry, vol. 67, no. 33, pp. 9286-9294.
Hubbard, TD, Liu, Q, Murray, IA, Dong, F, Miller, C, Smith, PB, Gowda, K, Lin, JM, Amin, S, Patterson, AD & Perdew, GH 2019, 'Microbiota Metabolism Promotes Synthesis of the Human Ah Receptor Agonist 2,8-Dihydroxyquinoline', Journal of Proteome Research, vol. 18, no. 4, pp. 1715-1724.
Singh, V, Yeoh, BS, Walker, RE, Xiao, X, Saha, P, Golonka, RM, Cai, J, Bretin, ACA, Cheng, X, Liu, Q, Flythe, MD, Chassaing, B, Shearer, GC, Patterson, AD, Gewirtz, AT & Vijay-Kumar, M 2019, 'Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation', Gut, vol. 68, no. 10, pp. 1801-1812.
Chagwedera, DN, Ang, QY, Bisanz, JE, Leong, YA, Ganeshan, K, Cai, J, Patterson, AD, Turnbaugh, PJ & Chawla, A 2019, 'Nutrient Sensing in CD11c Cells Alters the Gut Microbiota to Regulate Food Intake and Body Mass', Cell Metabolism, vol. 30, no. 2, pp. 364-373.e7.
Qi, X, Yun, C, Sun, L, Xia, J, Wu, Q, Wang, Y, Wang, L, Zhang, Y, Liang, X, Wang, L, Gonzalez, FJ, Patterson, AD, Liu, H, Mu, L, Zhou, Z, Zhao, Y, Li, R, Liu, P, Zhong, C, Pang, Y, Jiang, C & Qiao, J 2019, 'Publisher Correction: Gut microbiota–bile acid–interleukin-22 axis orchestrates polycystic ovary syndrome (Nature Medicine, (2019), 25, 8, (1225-1233), 10.1038/s41591-019-0509-0)', Nature Medicine, vol. 25, no. 9, pp. 1459.
Snyder, LM, McDaniel, KL, Tian, Y, Wei, CH, Kennett, MJ, Patterson, AD, Catharine Ross, A & Cantorna, MT 2019, 'Retinoic acid mediated clearance of Citrobacter rodentium in vitamin A deficient mice requires CD11b+ and T cells', Frontiers in immunology, vol. 10, no. JAN, 3090.
Zheng, S, Loreto, R, Smith, P, Patterson, A, Hughes, D & Wang, L 2019, 'Specialist and generalist fungal parasites induce distinct biochemical changes in the mandible muscles of their host', International journal of molecular sciences, vol. 20, no. 18, 4589.
Bao, L, Festa, F, Freet, CS, Lee, JP, Hirschler-Laszkiewicz, IM, Chen, SJ, Keefer, KA, Wang, HG, Patterson, AD, Cheung, JY & Miller, BA 2019, 'The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2', Scientific reports, vol. 9, no. 1, 14132.
Peters, JM, Walter, V, Patterson, AD & Gonzalez, FJ 2019, 'Unraveling the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) expression in colon carcinogenesis', npj Precision Oncology, vol. 3, no. 1, 26.
Cantorna, MT, Lin, YD, Arora, J, Bora, S, Tian, Y, Nichols, RG & Patterson, AD 2019, 'Vitamin D Regulates the Microbiota to Control the Numbers of RORγt/FoxP3+ Regulatory T Cells in the Colon', Frontiers in immunology, vol. 10, pp. 1772.