Researcher Profile

Researcher Profile

Achuthamangalam Madhankumar, MS, PhD

Achuthamangalam Madhankumar, MS, PhD

Assistant Professor, Department of Neurosurgery
Scientific Program:Experimental Therapeutics
abm10@psu.edu

Research Interests

  • Neoplasms
  • Interleukin-13
  • Glioma
  • Interleukin-13 Receptors
  • Therapeutics
  • Liposomes
  • Exosomes
  • Doxorubicin
  • Proteins
  • Neurilemmoma
  • Apoferritins
  • Brain Neoplasms

Recent Publications

2019

Payne, R, Mrowczynski, OD, Slagle-Webb, B, Bourcier, A, Mau, C, Aregawi, D, Madhankumar, A, Lee, SY, Harbaugh, K, Connor, J & Rizk, E 2019, 'MLN8237 treatment in an orthoxenograft murine model for malignant peripheral nerve sheath tumors', Journal of neurosurgery, vol. 130, no. 2, pp. 465-475. https://doi.org/10.3171/2017.8.JNS17765

2018

Mrowczynski, OD, Madhankumar, A, Sundstrom, J, Zhao, Y, Imamura, Y, Slagle-Webb, B, Mau, C, Payne, RA, Rizk, E, Zacharia, B & Connor, J 2018, 'Exosomes impact survival to radiation exposure in cell line models of nervous system cancer', Oncotarget, vol. 9, no. 90, pp. 36083-36101.
Madhankumar, A, Mrowczynski, OD, Slagle-Webb, B, Ravi, V, Bourcier, AJ, Payne, R, Harbaugh, K, Rizk, E & Connor, J 2018, 'Tumor targeted delivery of doxorubicin in malignant peripheral nerve sheath tumors', PloS one, vol. 13, no. 1, e0181529. https://doi.org/10.1371/journal.pone.0181529

2017

Mrowczynski, OD, Madhankumar, A, Slagle-Webb, B, Lee, S, Zacharia, B & Connor, J 2017, 'HFE genotype affects exosome phenotype in cancer', Biochimica et Biophysica Acta - General Subjects, vol. 1861, no. 8, pp. 1921-1928. https://doi.org/10.1016/j.bbagen.2017.05.014
Madhankumar, A, Mrowczynski, OD, Patel, SR, Weston, CL, Zacharia, B, Glantz, M, Siedlecki, C, Xu, L & Connor, J 2017, 'Interleukin-13 conjugated quantum dots for identification of glioma initiating cells and their extracellular vesicles', Acta Biomaterialia, vol. 58, pp. 205-213. https://doi.org/10.1016/j.actbio.2017.06.002

2016

Liu, X, Madhankumar, A, Miller, PA, Duck, KA, Hafenstein, S, Rizk, E, Slagle-Webb, B, Sheehan, JM, Connor, J & Yang, Q 2016, 'MRI contrast agent for targeting glioma: Interleukin-13 labeled liposome encapsulating gadolinium-DTPA', Neuro-Oncology, vol. 18, no. 5, pp. 691-699. https://doi.org/10.1093/neuonc/nov263

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)