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Ruobo Zhou

Ruobo Zhou

Assistant Professor, Chemistry
Penn State Neuroscience Institute
Scientific Program:Mechanisms of Carcinogenesis
RKZ5110@psu.edu

Recent Publications

2026

Zheng, Y, Fei, J, Chakrabarti, A & Zhou, R 2026, 'A Chemically Inducible Multimerization System for Tunable and Background-Free RTK Activation', Analytical Chemistry, vol. 98, no. 2, pp. 1328-1341. https://doi.org/10.1021/acs.analchem.5c05190
Li, L, Feng, X, Fang, F, Fei, J, Lu, J, Zhang, H, Ždímalová, MD, Yuan, Y, Luo, Z, Huang, H, Liu, D, Huang, F, Liu, H, Zeng, Y, Bian, F, Ma, M, You, IJ, Liu, L, Yan, X, Li, M, Lin, Y, Xie, Q, Krish, A, Duan, X, Goldberg, JL, Chen, X, Braun, M, Lansky, Z, Han, Y, Zhou, R & Hu, Y 2026, 'Actin depolymerization promotes axon regeneration by restoring axonal mitochondrial transport in mouse models of optic neuropathy', Science Translational Medicine, vol. 18, no. 838, eadw0908. https://doi.org/10.1126/scitranslmed.adw0908
Tao, Y & Zhou, R 2026, 'CLaSSiNet: A Computational Framework for High-Resolution Classification and Spatial Mapping of Heterogeneous Biological Network Architectures', JACS Au, vol. 6, no. 4, pp. 2637-2655. https://doi.org/10.1021/jacsau.5c01775
Sha, Z, Pedley, AM, Iles, TD, Zhang, S, Staub, JR, Zhou, R & Benkovic, SJ 2026, 'Coordination of cell organelles to promote metabolon formation', Proceedings of the National Academy of Sciences of the United States of America, vol. 123, no. 5, e2532504123. https://doi.org/10.1073/pnas.2532504123
Zhang, H, Yao, Y, Wang, X, Zheng, Y, Zhang, S, Tao, Y, Yang, H, Wang, Y, Liu, M, Feric, M & Zhou, R 2026, 'FLEXTAG: a small and self-renewable protein labeling system for anti-fading multi-color super-resolution imaging', Nature communications, vol. 17, no. 1, 2156. https://doi.org/10.1038/s41467-026-69658-9
Fei, J, Zheng, Y, LaLonde, C, Tao, Y & Zhou, R 2026, 'Membrane-associated periodic skeleton regulates major forms of endocytosis in neurons through a signaling-driven positive feedback loop', Science Advances, vol. 12, no. 7, eaeb0803. https://doi.org/10.1126/sciadv.aeb0803

2025

Gao, J, Li, H, Tan, S, Zhou, R & Lee, TH 2025, 'Roles of histone chaperone Nap1 and histone acetylation in regulating phase-separation of nucleosome arrays', Nature communications, vol. 16, no. 1, 10672. https://doi.org/10.1038/s41467-025-65701-3

2023

Fei, J & Zhou, R 2023, 'Watching biomolecules stride in real time', Science, vol. 379, no. 6636, pp. 986-987. https://doi.org/10.1126/science.adg8451

2022

Zhou, R, Han, B, Nowak, R, Lu, Y, Heller, E, Xia, C, Chishti, AH, Fowler, VM & Zhuang, X 2022, 'Proteomic and functional analyses of the periodic membrane skeleton in neurons', Nature communications, vol. 13, no. 1, 3196. https://doi.org/10.1038/s41467-022-30720-x