Irina Elcheva, PhD - Penn State Cancer Institute
Researcher Profile
Irina Elcheva, PhD
Assistant Professor, Department of Pediatrics
Division of Hematology and Oncology
Penn State Neuroscience Institute
Division of Hematology and Oncology
Penn State Neuroscience Institute
Scientific Program:Mechanisms of Carcinogenesis
Recent Publications
2023
Singh, V, Walter, V, Elcheva, I, Imamura Kawasawa, Y & Spiegelman, VS 2023, 'Global role of IGF2BP1 in controlling the expression of Wnt/β-catenin-regulated genes in colorectal cancer cells', Frontiers in Cell and Developmental Biology, vol. 11, 1236356. https://doi.org/10.3389/fcell.2023.1236356
Elcheva, IA, Gowda, CP, Bogush, D, Gornostaeva, S, Fakhardo, A, Sheth, N, Kokolus, KM, Sharma, A, Dovat, S, Uzun, Y, Schell, TD & Spiegelman, VS 2023, 'IGF2BP family of RNA-binding proteins regulate innate and adaptive immune responses in cancer cells and tumor microenvironment', Frontiers in immunology, vol. 14, 1224516. https://doi.org/10.3389/fimmu.2023.1224516
2022
Liu, Z & Elcheva, I 2022, 'A six-gene prognostic signature for both adult and pediatric acute myeloid leukemia identified with machine learning', American Journal of Translational Research, vol. 14, no. 9, pp. 6210-6221. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556437/>
McLaughlin, C, Datta, P, Singh, YP, Lo, A, Horchler, S, Elcheva, IA, Ozbolat, IT, Ravnic, DJ & Koduru, SV 2022, 'Mesenchymal Stem Cell-Derived Extracellular Vesicles for Therapeutic Use and in Bioengineering Applications', Cells, no. 21, 3366. https://doi.org/10.3390/cells11213366
2021
Golla, U, Ehudin, MA, Annageldiyev, C, Zeng, Z, Bastihalli Tukaramrao, D, Tarren, A, Date, AA, Elcheva, I, Berg, A, Amin, S, Loughran, TP, Kester, M, Desai, D, Dovat, S, Claxton, D & Sharma, A 2021, 'Dj4 targets the rho-associated protein kinase pathway and attenuates disease progression in preclinical murine models of acute myeloid leukemia', Cancers, vol. 13, no. 19, 4889. https://doi.org/10.3390/cancers13194889
Koduru, SV, Elcheva, IA, Leberfinger, AN & Ravnic, DJ 2021, 'In silico analysis of RNA and small RNA sequencing data from human BM-MSCs and differentiated osteocytes, chondrocytes and tenocytes', Engineered Regeneration, vol. 2, pp. 19-30. https://doi.org/10.1016/j.engreg.2020.12.002
Elcheva, IA & Spiegelman, VS 2021, 'Targeting RNA-binding proteins in acute and chronic leukemia', Leukemia, vol. 35, no. 2, pp. 360-376. https://doi.org/10.1038/s41375-020-01066-4
2020
Elcheva, IA & Spiegelman, VS 2020, 'The role of cis-and trans-acting rna regulatory elements in leukemia', Cancers, vol. 12, no. 12, 3854, pp. 1-30. https://doi.org/10.3390/cancers12123854
Galat, Y, Perepitchka, M, Elcheva, I, Iannaccone, S, Iannaccone, PM & Galat, V 2020, 'iPSC-derived progenitor stromal cells provide new insights into aberrant musculoskeletal development and resistance to cancer in down syndrome', Scientific reports, vol. 10, no. 1, 13252. https://doi.org/10.1038/s41598-020-69418-9