Raghu Sinha, MS, PhD - Penn State Cancer Institute
Researcher Profile
Raghu Sinha, MS, PhD
Associate Professor, Department of Biochemistry and Molecular Biology
Penn State Center for Research on Tobacco and Health
Penn State Center for Research on Tobacco and Health
Scientific Program:Cancer Control
Research Interests
- Proteins
- Selenium
- Neoplasms
- Breast Neoplasms
- In Vitro Techniques
- Biomarkers
- Prostatic Neoplasms
- Growth
- Epithelial Cells
- selenomethylselenocysteine
- Chemoprevention
- Organoselenium Compounds
Recent Publications
2024
Kori, M, Demirtas, TY, Comertpay, B, Arga, KY, Sinha, R & Gov, E 2024, 'A 19-Gene Signature of Serous Ovarian Cancer Identified by Machine Learning and Systems Biology: Prospects for Diagnostics and Personalized Medicine', OMICS A Journal of Integrative Biology, vol. 28, no. 2, pp. 90-101. https://doi.org/10.1089/omi.2023.0273
2023
Richie, JP, Sinha, R, Dong, Z, Nichenametla, SN, Ables, GP, Ciccarella, A, Sinha, I, Calcagnotto, AM, Chinchilli, VM, Reinhart, L & Orentreich, D 2023, 'Dietary Methionine and Total Sulfur Amino Acid Restriction in Healthy Adults', Journal of Nutrition, Health and Aging, vol. 27, no. 2, pp. 111-123. https://doi.org/10.1007/s12603-023-1883-3
Sinha, I, Fogle, RL, Gulfidan, G, Stanley, AE, Walter, V, Hollenbeak, CS, Arga, KY & Sinha, R 2023, 'Potential Early Markers for Breast Cancer: A Proteomic Approach Comparing Saliva and Serum Samples in a Pilot Study', International journal of molecular sciences, vol. 24, no. 4, 4164. https://doi.org/10.3390/ijms24044164
Sinha, I, Zhu, J & Sinha, R 2023, 'Selective Impact of Selenium Compounds on Two Cytokine Storm Players', Journal of Personalized Medicine, vol. 13, no. 10, 1455. https://doi.org/10.3390/jpm13101455
2022
Kori, M, Ozdemir, GE, Arga, KY & Sinha, R 2022, 'A Pan-Cancer Atlas of Differentially Interacting Hallmarks of Cancer Proteins', Journal of Personalized Medicine, vol. 12, no. 11, 1919. https://doi.org/10.3390/jpm12111919
Ma, L, Xiu, G, Muscat, J, Sinha, R, Sun, D & Xiu, G 2022, 'Comparative proteomic analysis of exhaled breath condensate between lung adenocarcinoma and CT-detected benign pulmonary nodule patients', Cancer Biomarkers, vol. 34, no. 2, pp. 163-174. https://doi.org/10.3233/CBM-203269
Sinha, I, Goel, R, Bitzer, ZT, Trushin, N, Liao, J & Sinha, R 2022, 'Evaluating electronic cigarette cytotoxicity and inflammatory responses in vitro', Tobacco Induced Diseases, vol. 20, no. 5, 45. https://doi.org/10.18332/tid/147200
Wooten, DJ, Sinha, I & Sinha, R 2022, 'Selenium Induces Pancreatic Cancer Cell Death Alone and in Combination with Gemcitabine', Biomedicines, vol. 10, no. 1, 149. https://doi.org/10.3390/biomedicines10010149
2021
Dong, Z, Gao, X, Chinchilli, VM, Sinha, R, Muscat, J, Winkels, R & Richie, JP 2022, 'Association of dietary sulfur amino acid intake with mortality from diabetes and other causes', European Journal of Nutrition, vol. 61, no. 1, pp. 289-298. https://doi.org/10.1007/s00394-021-02641-w
Sinha, I, Modesto, J, Krebs, NM, Stanley, AE, Walter, VA, Richie, JP, Muscat, JE & Sinha, R 2021, 'Changes in salivary proteome before and after cigarette smoking in smokers compared to sham smoking in nonsmokers: A pilot study', Tobacco Induced Diseases, vol. 19, 138336. https://doi.org/10.18332/TID/138336
Turanli, B, Yildirim, E, Gulfidan, G, Arga, KY & Sinha, R 2021, 'Current state of “omics” biomarkers in pancreatic cancer', Journal of Personalized Medicine, vol. 11, no. 2, 127, pp. 1-24. https://doi.org/10.3390/jpm11020127
Gulfidan, G, Beklen, H, Sinha, I, Kucukalp, F, Caloglu, B, Esen, I, Turanli, B, Ayyildiz, DI, Arga, KY & Sinha, R 2021, 'Differential Protein Interactome in Esophageal Squamous Cell Carcinoma Offers Novel Systems Biomarker Candidates with High Diagnostic and Prognostic Performance', OMICS A Journal of Integrative Biology, vol. 25, no. 8, pp. 495-512. https://doi.org/10.1089/omi.2021.0085
Caliskan, A, Gulfidan, G, Sinha, R & Arga, KY 2021, 'Differential interactome proposes subtype-specific biomarkers and potential therapeutics in renal cell carcinomas', Journal of Clinical Medicine, vol. 11, no. 2, 158, pp. 1-12. https://doi.org/10.3390/jpm11020158
Ma, L, Muscat, JE, Sinha, R, Sun, D & Xiu, G 2021, 'Proteomics of exhaled breath condensate in lung cancer and controls using data-independent acquisition (DIA): A pilot study', Journal of Breath Research, vol. 15, no. 2, 026002. https://doi.org/10.1088/1752-7163/abd07e
Arga, KY & Sinha, R 2021, 'Recent developments in cancer systems biology: Lessons learned and future directions', Journal of Personalized Medicine, vol. 11, no. 4, 271. https://doi.org/10.3390/jpm11040271
2020
Dong, Z, Gao, X, Chinchilli, VM, Sinha, R, Muscat, J, Winkels, RM & Richie, JP 2020, 'Association of sulfur amino acid consumption with cardiometabolic risk factors: Cross-sectional findings from NHANES III', EClinicalMedicine, vol. 19, 100248. https://doi.org/10.1016/j.eclinm.2019.100248
Gulfidan, G, Turanli, B, Beklen, H, Sinha, R & Arga, KY 2020, 'Pan-cancer mapping of differential protein-protein interactions', Scientific reports, vol. 10, no. 1, 3272. https://doi.org/10.1038/s41598-020-60127-x