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Patricia

Patricia "Sue" Grigson-Kennedy, MS, PhD

Professor and Chair, Department of Neural and Behavioral Sciences
Interim Chair, Department of Pharmacology
Penn State Neuroscience Institute
Scientific Program:Cancer Control
PSG6@psu.edu
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Research Interests

Dr. Sue Grigson’s research focuses on substance abuse and addiction. She has been continuously funded by the National Institutes of Health (NIH) for more than 28 years and is the recipient of an NIH MERIT award, which recognizes the top tier of research funded by the NIH.

She is the inaugural director of Penn State Addiction Center for Translation.

  • Pharmaceutical Preparations
  • Reward
  • Cues
  • Cocaine
  • Saccharin
  • Sucrose
  • Heroin
  • Self Administration
  • Substance-Related Disorders
  • Morphine
  • Lithium Chloride
  • Parabrachial Nucleus

Recent Publications

2024

Freet, CS, Evans, B, Brick, TR, Deneke, E, Wasserman, EJ, Ballard, SM, Stankoski, DM, Kong, L, Raja-Khan, N, Nyland, JE, Arnold, AC, Krishnamurthy, VB, Fernandez-Mendoza, J, Cleveland, HH, Scioli, AD, Molchanow, A, Messner, AE, Ayaz, H, Grigson, PS & Bunce, SC 2024, 'Ecological momentary assessment and cue-elicited drug craving as primary endpoints: study protocol for a randomized, double-blind, placebo-controlled clinical trial testing the efficacy of a GLP-1 receptor agonist in opioid use disorder', Addiction science & clinical practice, vol. 19, no. 1, 56. https://doi.org/10.1186/s13722-024-00481-7

2023

McLaughlin, PJ, West, EA, Grigson, PS & Hobkirk, AL 2023, 'Addiction III: From mouse to man', Brain Research Bulletin, vol. 193, pp. 22-26. https://doi.org/10.1016/j.brainresbull.2022.12.001
Fang, J, Miller, P & Grigson, PS 2023, 'Sleep is increased by liraglutide, a glucagon-like peptide-1 receptor agonist, in rats', Brain Research Bulletin, vol. 192, pp. 142-155. https://doi.org/10.1016/j.brainresbull.2022.11.012

2022

Douton, JE, Acharya, NK, Stoltzfus, B, Sun, D, Grigson, PS & Nyland, JE 2022, 'Acute glucagon-like peptide-1 receptor agonist liraglutide prevents cue-, stress-, and drug-induced heroin-seeking in rats', Behavioural Pharmacology, vol. 33, no. 5, pp. 364-378. https://doi.org/10.1097/FBP.0000000000000685
Urbanik, LA, Acharya, NK & Grigson, PS 2022, 'Acute treatment with the glucagon-like peptide-1 receptor agonist, liraglutide, reduces cue- and drug-induced fentanyl seeking in rats', Brain Research Bulletin, vol. 189, pp. 155-162. https://doi.org/10.1016/j.brainresbull.2022.08.023
McFalls, AJ, Imperio, CG, Woodward, E, Krikorian, C, Stoltsfus, B, Wronowski, B, Grigson, PS, Freeman, WM & Vrana, KE 2022, 'An RNA-seq study of the mPFC of rats with different addiction phenotypes', Brain Research Bulletin, vol. 191, pp. 107-120. https://doi.org/10.1016/j.brainresbull.2022.09.023
Evans, B, Stoltzfus, B, Acharya, N, Nyland, JE, Arnold, AC, Freet, CS, Bunce, SC & Grigson, PS 2022, 'Dose titration with the glucagon-like peptide-1 agonist, liraglutide, reduces cue- and drug-induced heroin seeking in high drug-taking rats', Brain Research Bulletin, vol. 189, pp. 163-173. https://doi.org/10.1016/j.brainresbull.2022.08.022
McFalls, AJ, Jenney, C, Stanford, RS, Woodward, E, Hajnal, A, Grigson, PS & Vrana, KE 2022, 'Greater avoidance of a saccharin cue paired with passive delivery of heroin is associated with a select increase in expression of CRFR2 and CRFbp in the hippocampus in rats', Brain Research Bulletin, vol. 191, pp. 48-60. https://doi.org/10.1016/j.brainresbull.2022.10.009
Yingst, JM, Lester, C, Livelsberger, C, Allen, SI, Hammett, E, Veldheer, S, Hummer, B, Bordner, C, Zhu, J, Sciamanna, CN, Trushin, N, Tan, HS, Wilson, SJ, Twining, RC, Foulds, J & Grigson, PS 2022, 'Pilot randomized controlled trial evaluating the effect of random nicotine delivery on cigarettes per day and smoke exposure', Brain Research Bulletin, vol. 188, pp. 30-37. https://doi.org/10.1016/j.brainresbull.2022.07.017

2021

Kamens, HM, Miller, CN, Caulfield, JI, Zeid, D, Horton, WJ, Silva, CP, Sebastian, A, Albert, I, Gould, TJ, Fishbein, D, Grigson, PS & Cavigelli, SA 2021, 'Adolescent Stress Reduces Adult Morphine-Induced Behavioral Sensitization in C57BL/6J Mice', Frontiers in Behavioral Neuroscience, vol. 15, 678102. https://doi.org/10.3389/fnbeh.2021.678102
Nyland, JE, Raja-Khan, NT, Bettermann, K, Haouzi, PA, Leslie, DL, Kraschnewski, JL, Parent, LJ & Grigson, PS 2021, 'Diabetes, Drug Treatment, and Mortality in COVID-19: A Multinational Retrospective Cohort Study', Diabetes, vol. 70, no. 12, pp. 2903-2916. https://doi.org/10.2337/db21-0385
Douton, JE, Norgren, R & Grigson, PS 2021, 'Effects of a glucagon-like peptide-1 analog on appetitive and consummatory behavior for rewarding and aversive gustatory stimuli in rats', Physiology and Behavior, vol. 229, 113279. https://doi.org/10.1016/j.physbeh.2020.113279
Douton, JE, Augusto, C, Stoltzfus, B, Carkaci-Salli, N, Vrana, KE & Grigson, PS 2021, 'Glucagon-like peptide-1 receptor agonist, exendin-4, reduces reinstatement of heroin-seeking behavior in rats', Behavioural Pharmacology, vol. 32, no. 4, pp. 265-277. https://doi.org/10.1097/FBP.0000000000000609
Douton, JE, Horvath, N, Mills-Huffnagle, S, Nyland, JE, Hajnal, A & Grigson, PS 2022, 'Glucagon-like peptide-1 receptor agonist, liraglutide, reduces heroin self-administration and drug-induced reinstatement of heroin-seeking behaviour in rats', Addiction Biology, vol. 27, no. 2, e13117. https://doi.org/10.1111/adb.13117

2020

McKendrick, G, Garrett, H, Tanniru, S, Ballard, S, Sun, D, Silberman, Y, Grigson, PS & Graziane, NM 2020, 'A novel method to study reward-context associations and drug-seeking behaviors', Journal of Neuroscience Methods, vol. 343, 108857. https://doi.org/10.1016/j.jneumeth.2020.108857