Monika Joshi, MD, MRCP - Penn State Cancer Institute
Researcher Profile
Monika Joshi, MD, MRCP
Associate Professor, Department of Medicine
Endowed Associate Professor in Cancer Clinical Investigation, Department of Medicine
Endowed Professor in Cancer Clinical Investigation, Department of Medicine
Division of Hematology and Oncology
Assistant Professor, Department of Medicine
Endowed Associate Professor in Cancer Clinical Investigation, Department of Medicine
Endowed Professor in Cancer Clinical Investigation, Department of Medicine
Division of Hematology and Oncology
Assistant Professor, Department of Medicine
Scientific Program:Next-Generation Therapies
Disease Teams:
Cancer Institute, Genitourinary Cancer Team
Research Interests
Dr. Monika Joshi’s research focus is in the field of genitourinary tumors, particularly in the field of immunotherapy and targeted therapy.
- Therapeutics
- Neoplasms
- Carcinoma
- Urinary Bladder Neoplasms
- Survival
- Drug Therapy
- Prostatic Neoplasms
- Non-Small Cell Lung Carcinoma
- Immunotherapy
- Progression-Free Survival
- Renal Cell Carcinoma
- Radiotherapy
Clinical Trials
Parallel Phase III Randomized Trials of Genomic-Risk Stratified Unfavorable Intermediate Risk Prostate Cancer: De-Intensification and Intensification Clinical Trial Evaluation (GUIDANCE)
Angelica Herbal Supplement AGN-CognI.Q Acute Dose Safety and Pharmacokinetics (PK) Dose-Response in Prostate Cancer Patients (PK Dose Trial)
NRG-GU011: A Phase II Double-Blinded, Placebo-Controlled Trial of PROstate OligoMETastatic RadiotHErapy With or Without ANdrogen Deprivation Therapy in Oligometastatic Prostate Cancer (NRG Promethean)
Phase III Randomized Trial of Stereotactic ablative radiotherapy (SAbR) for Oligometastatic Advanced Renal Carcinoma (SOAR)
A Phase III Randomized, Open-Label, Multicenter Study to Determine the Efficacy and Safety of Durvalumab in Combination With Tremelimumab and Enfortumab Vedotin or Durvalumab in Combination With Enfortumab Vedotin for Perioperative Treatment in Patients Ineligible for Cisplatin Undergoing Radical Cystectomy for Muscle Invasive Bladder Cancer (VOLGA)
A Phase II/III trial of Durvalumab and Chemotherapy for Patients with High Grade Upper Tract Urothelial Cancer Prior to Nephroureterectomy EA8192
Evaluation of Biomarkers in Bladder Cancer Patients in the Neoadjuvant Setting
Phase III Study of PET-Directed Local or Systemic Therapy Intensification in Prostate Cancer Patients with Post-Prostatectomy Biochemical Recurrence
A Dose-Escalation and Expansion Study of the Safety and Efficacy of XL092 in Combination With Immuno-Oncology Agents in Subjects With Unresectable Advanced or Metastatic Solid Tumors
A Randomized Phase III Trial of Intravesical BCG veRsus Intravesical Docetaxel and GEmcitabine Treatment in BCG Naïve High Grade Non-Muscle Invasive Bladder Cancer (BRIDGE) EA8212
APG-115 - A Phase Ib/II Study of APG-115 in Combination with Pembrolizumab in Patients with Unresectable or Metastatic Melanomas or Advanced Solid Tumors
Parallel Phase III Randomized Trials for High Risk Prostate Cancer Evaluating De-Intensification for Lower Genomic Risk and Intensification of Concurrent Therapy for Higher Genomic Risk with Radiation (PREDICT-RT*)
Phase 1/2 Multicenter Study of the Safety, Pharmacokinetics, and Preliminary Efficacy of APL-101 in Subjects with Non-Small Cell Lung Cancer with c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
NRG-GU013: The Phase III 'High Five Trial' Five Fraction Radiation for High-Risk Prostate Cancer
One Time Tissue and Blood Collection from Patients with Lung Cancer at Risk for Developing Lung Cancer
The COVID-19 and Cancer Consortium (CCC19) Registry
Recent Publications
2024
Zakharia, Y, Singer, EA, Acharyya, S, Garje, R, Joshi, M, Peace, D, Baladandayuthapani, V, Majumdar, A, Li, X, Lalancette, C, Kryczek, I, Zou, W & Alva, A 2024, 'Durvalumab and guadecitabine in advanced clear cell renal cell carcinoma: results from the phase Ib/II study BTCRC-GU16-043', Nature communications, vol. 15, no. 1, 972. https://doi.org/10.1038/s41467-024-45216-z
Holder, S, Yin, M & Joshi, M 2024, 'Editorial: Innovative molecular therapeutic approaches in urothelial carcinoma', Frontiers in Oncology, vol. 14, 1430285. https://doi.org/10.3389/fonc.2024.1430285
Mittal, K & Joshi, M 2024, 'FGFR inhibitors in urothelial cancer: Contextualizing THOR within the new treatment landscape', Med, vol. 5, no. 3, pp. 176-178. https://doi.org/10.1016/j.medj.2023.12.008
Segel, JE, Wong, WG, Kaag, M, Joshi, M, Warrick, J, Lengerich, EJ & Shen, C 2024, 'Relationship Between Availability of Urologists and Primary Care Providers and Stage of Diagnosis for Invasive Urinary Bladder Cancer', Urology Practice, vol. 11, no. 2, pp. 339-346. https://doi.org/10.1097/UPJ.0000000000000503
Castellano, CA, Sun, T, Ravindranathan, D, Hwang, C, Balanchivadze, N, Singh, SRK, Griffiths, EA, Puzanov, I, Ruiz-Garcia, E, Vilar-Compte, D, Cárdenas-Delgado, AI, McKay, RR, Nonato, TK, Ajmera, A, Yu, PP, Nadkarni, R, O’Connor, TE, Berg, S, Ma, K, Farmakiotis, D, Vieira, K, Arvanitis, P, Saliby, RM, Labaki, C, El Zarif, T, Wise-Draper, TM, Zamulko, O, Li, N, Bodin, BE, Accordino, MK, Ingham, M, Joshi, M, Polimera, HV, Fecher, LA, Friese, CR, Yoon, JJ, Mavromatis, BH, Brown, JT, Russell, K, Nanchal, R, Singh, H, Tachiki, L, Moria, FA, Nagaraj, G, Cortez, K, Abbasi, SH, Wulff-Burchfield, EM, Puc, M, Weissmann, LB, Bhatt, PS, Mariano, MG, Mishra, S, Halabi, S, Beeghly, A, Warner, JL, French, B & Bilen, MA 2024, 'The impact of cancer metastases on COVID-19 outcomes: A COVID-19 and Cancer Consortium registry-based retrospective cohort study', Cancer, vol. 130, no. 12, pp. 2191-2204. https://doi.org/10.1002/cncr.35247
2023
Ledford, SG, Moss, JL, Alles, S, Wang, M, Kessler, FC, Marks, B, Soliman, AS, Joshi, MD & Lengerich, EJ 2023, 'Behaviors and Advocacy Related to COVID-19 among Cancer Patients: The Health Belief Model and Opportunities for Messaging and Education', Journal of Cancer Education, vol. 38, no. 5, pp. 1690-1696. https://doi.org/10.1007/s13187-023-02323-7
Choueiri, TK, Labaki, C, Bakouny, Z, Hsu, CY, Schmidt, AL, de Lima Lopes, G, Hwang, C, Singh, SRK, Jani, C, Weissmann, LB, Griffiths, EA, Halabi, S, Wu, U, Berg, S, O'Connor, TE, Wise-Draper, TM, Panagiotou, OA, Klein, EJ, Joshi, M, Yared, F, Dutra, MS, Gatson, NTN, Blau, S, Singh, H, Nanchal, R, McKay, RR, Nonato, TK, Quinn, R, Rubinstein, SM, Puc, M, Mavromatis, BH, Vikas, P, Faller, B, Zaren, HA, Del Prete, S, Russell, K, Reuben, DY, Accordino, MK, Friese, CR, Mishra, S, Rivera, DR, Shyr, Y, Farmakiotis, D & Warner, JL 2023, 'Breakthrough SARS-CoV-2 infections among patients with cancer following two and three doses of COVID-19 mRNA vaccines: a retrospective observational study from the COVID-19 and Cancer Consortium', The Lancet Regional Health - Americas, vol. 19, 100445. https://doi.org/10.1016/j.lana.2023.100445
COVID-19 and Cancer Consortium 2023, 'Clinical characteristics, racial inequities, and outcomes in patients with breast cancer and COVID-19: A COVID-19 and cancer consortium (CCC19) cohort study', eLife, vol. 12, e82618. https://doi.org/10.7554/ELIFE.82618
Joshi, M, Tuanquin, L, Zhu, J, Walter, V, Schell, T, Kaag, M, Kilari, D, Liao, J, Holder, SL, Emamekhoo, H, Sankin, A, Merrill, S, Zheng, H, Warrick, J, Hauke, R, Gartrel, B, Stein, M, Drabick, J, Degraff, DJ & Zakharia, Y 2023, 'Concurrent durvalumab and radiation therapy (DUART) followed by adjuvant durvalumab in patients with localized urothelial cancer of bladder: Results from phase II study, BTCRC-GU15-023', Journal for ImmunoTherapy of Cancer, vol. 11, no. 2, e006551. https://doi.org/10.1136/jitc-2022-006551
Mittal, K, Sheen, M, Wheelden, M, Faramand, R, Teplinsky, E & Joshi, M 2023, 'Dobbs v Jackson - Rewriting Women's Autonomy in Cancer Care', JCO Oncology Practice, vol. 19, no. 4, pp. 157-159. https://doi.org/10.1200/OP.22.00610
Lü, J, Jiang, C, Joshi, M & Drabick, JJ 2023, Giant Angelica: Angelica gigas Nakai – Herbal Giant’s Anticancer Potential. in Ancient and Traditional Foods, Plants, Herbs and Spices used in Cancer. CRC Press, pp. 165-180. https://doi.org/10.1201/9781003260028-15
COVID-19 and Cancer Consortium 2023, 'Impact of COVID-19 in patients on active melanoma therapy and with history of melanoma', BMC Cancer, vol. 23, no. 1, 265. https://doi.org/10.1186/s12885-023-10708-6
Bakouny, Z, Labaki, C, Grover, P, Awosika, J, Gulati, S, Hsu, CY, Alimohamed, SI, Bashir, B, Berg, S, Bilen, MA, Bowles, D, Castellano, C, Desai, A, Elkrief, A, Eton, OE, Fecher, LA, Flora, D, Galsky, MD, Gatti-Mays, ME, Gesenhues, A, Glover, MJ, Gopalakrishnan, D, Gupta, S, Halfdanarson, TR, Hayes-Lattin, B, Hendawi, M, Hsu, E, Hwang, C, Jandarov, R, Jani, C, Johnson, DB, Joshi, M, Khan, H, Khan, SA, Knox, N, Koshkin, VS, Kulkarni, AA, Kwon, DH, Matar, S, McKay, RR, Mishra, S, Moria, FA, Nizam, A, Nock, NL, Nonato, TK, Panasci, J, Pomerantz, L, Portuguese, AJ, Provenzano, D, Puc, M, Rao, YJ, Rhodes, TD, Riely, GJ, Ripp, JJ, Rivera, AV, Ruiz-Garcia, E, Schmidt, AL, Schoenfeld, AJ, Schwartz, GK, Shah, SA, Shaya, J, Subbiah, S, Tachiki, LM, Tucker, MD, Valdez-Reyes, M, Weissmann, LB, Wotman, MT, Wulff-Burchfield, EM, Xie, Z, Yang, YJ, Thompson, MA, Shah, DP, Warner, JL, Shyr, Y, Choueiri, TK & Wise-Draper, TM 2023, 'Interplay of Immunosuppression and Immunotherapy among Patients with Cancer and COVID-19', JAMA Oncology, vol. 9, no. 1, pp. 128-134. https://doi.org/10.1001/jamaoncol.2022.5357
Siefker-Radtke, AO, Necchi, A, Park, SH, García-Donas, J, Huddart, RA, Burgess, EF, Fleming, MT, Rezazadeh Kalebasty, A, Mellado, B, Varlamov, S, Joshi, M, Duran, I, Tagawa, ST, Zakharia, Y, Qi, K, Akapame, S, Triantos, S, O'Hagan, A & Loriot, Y 2023, 'Management of Fibroblast Growth Factor Inhibitor Treatment–emergent Adverse Events of Interest in Patients with Locally Advanced or Metastatic Urothelial Carcinoma', European Urology Open Science, vol. 50, pp. 1-9. https://doi.org/10.1016/j.euros.2022.12.019
Venkatesulu, BP, Liauw, SL, Joshi, M, Baumann, BC, Yoo, R, Roupret, M, Choudhury, A, Efstathiou, JA, Murthy, V, Sargos, P & Solanki, AA 2023, 'Multidisciplinary Management and Radiotherapy Recommendations for Clinically and Pathologically Node-positive Bladder Cancer', Seminars in Radiation Oncology, vol. 33, no. 1, pp. 35-50. https://doi.org/10.1016/j.semradonc.2022.10.005
Tarango, R, Hadjiiski, L, Alva, A, Chan, HP, Cohan, RH, Caoili, EM, Cha, KH, Samala, RK, Weizer, AZ, Zhou, C, Joshi, M & Zakharia, Y 2023, Survival Prediction for Patients with Metastatic Urothelial Cancer after Immunotherapy using Machine Learning. in KM Iftekharuddin & W Chen (eds), Medical Imaging 2023: Computer-Aided Diagnosis., 124653A, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 12465, SPIE, Medical Imaging 2023: Computer-Aided Diagnosis, San Diego, United States, 2/19/23. https://doi.org/10.1117/12.2655482
Gulati, S, Hsu, CY, Shah, S, Shah, PK, Zon, R, Alsamarai, S, Awosika, J, El-Bakouny, Z, Bashir, B, Beeghly, A, Berg, S, De-La-Rosa-Martinez, D, Doroshow, DB, Egan, PC, Fein, J, Flora, DB, Friese, CR, Fromowitz, A, Griffiths, EA, Hwang, C, Jani, C, Joshi, M, Khan, H, Klein, EJ, Heater, NK, Koshkin, VS, Kwon, DH, Labaki, C, Latif, T, McKay, RR, Nagaraj, G, Nakasone, ES, Nonato, T, Polimera, HV, Puc, M, Razavi, P, Ruiz-Garcia, E, Saliby, RM, Shastri, A, Singh, SRK, Tagalakis, V, Vilar-Compte, D, Weissmann, LB, Wilkins, CR, Wise-Draper, TM, Wotman, MT, Yoon, JJ, Mishra, S, Grivas, P, Shyr, Y, Warner, JL, Connors, JM, Shah, DP & Rosovsky, RP 2023, 'Systemic Anticancer Therapy and Thromboembolic Outcomes in Hospitalized Patients with Cancer and COVID-19', JAMA Oncology, vol. 9, no. 10, pp. 1390-1400. https://doi.org/10.1001/jamaoncol.2023.2934
2022
Weng, X, Shen, C, Van Scoy, LJ, Boltz, M, Joshi, M & Wang, L 2022, 'A comparison of end-of-life care patterns between older patients with both cancer and Alzheimer's disease and related dementias versus those with only cancer', Journal of Geriatric Oncology, vol. 13, no. 8, pp. 1111-1121. https://doi.org/10.1016/j.jgo.2022.08.011
Weng, X, Shen, C, Vasekar, M, Boltz, M, Joshi, M, Van Scoy, LJ & Wang, L 2023, 'Alzheimer's disease and related dementias is a risk factor for lower utilization of breast cancer screening and unstaged cancer diagnosis: Observational study from SEER-Medicare 2004–2016 data', Journal of Geriatric Oncology, vol. 14, no. 3, 101407. https://doi.org/10.1016/j.jgo.2022.11.006
Lü, J, Jiang, C, Schell, TD, Joshi, M, Raman, JD & Xing, C 2022, 'Angelica gigas: Signature Compounds, In Vivo Anticancer, Analgesic, Neuroprotective and Other Activities, and the Clinical Translation Challenges', American Journal of Chinese Medicine, vol. 50, no. 6, pp. 1475-1527. https://doi.org/10.1142/S0192415X2250063X
Makrakis, D, Talukder, R, Lin, GI, Diamantopoulos, LN, Dawsey, S, Gupta, S, Carril-Ajuria, L, Castellano, D, de Kouchkovsky, I, Koshkin, VS, Park, JJ, Alva, A, Bilen, MA, Stewart, TF, McKay, RR, Tripathi, N, Agarwal, N, Vather-Wu, N, Zakharia, Y, Morales-Barrera, R, Devitt, ME, Cortellini, A, Fulgenzi, CAM, Pinato, DJ, Nelson, A, Hoimes, CJ, Gupta, K, Gartrell, BA, Sankin, A, Tripathi, A, Zakopoulou, R, Bamias, A, Murgic, J, Fröbe, A, Rodriguez-Vida, A, Drakaki, A, Liu, S, Lu, E, Kumar, V, Lorenzo, GD, Joshi, M, Isaacsson-Velho, P, Buznego, LA, Duran, I, Moses, M, Jang, A, Barata, P, Sonpavde, G, Yu, EY, Montgomery, RB, Grivas, P & Khaki, AR 2022, 'Association Between Sites of Metastasis and Outcomes With Immune Checkpoint Inhibitors in Advanced Urothelial Carcinoma', Clinical Genitourinary Cancer, vol. 20, no. 5, pp. e440-e452. https://doi.org/10.1016/j.clgc.2022.06.001
Talukder, R, Makrakis, D, Lin, GI, Diamantopoulos, LN, Dawsey, S, Gupta, S, Carril-Ajuria, L, Castellano, D, de Kouchkovsky, I, Jindal, T, Koshkin, VS, Park, JJ, Alva, A, Bilen, MA, Stewart, TF, McKay, RR, Tripathi, N, Agarwal, N, Vather-Wu, N, Zakharia, Y, Morales-Barrera, R, Devitt, ME, Cortellini, A, Fulgenzi, CAM, Pinato, DJ, Nelson, A, Hoimes, CJ, Gupta, K, Gartrell, BA, Sankin, A, Tripathi, A, Zakopoulou, R, Bamias, A, Murgic, J, Fröbe, A, Rodriguez-Vida, A, Drakaki, A, Liu, S, Lu, E, Kumar, V, Lorenzo, GD, Joshi, M, Isaacsson-Velho, P, Buznego, LA, Duran, I, Moses, M, Barata, P, Sonpavde, G, Wright, JL, Yu, EY, Montgomery, RB, Hsieh, AC, Grivas, P & Khaki, AR 2022, 'Association of the Time to Immune Checkpoint Inhibitor (ICI) Initiation and Outcomes With Second Line ICI in Patients With Advanced Urothelial Carcinoma', Clinical Genitourinary Cancer, vol. 20, no. 6, pp. 558-567. https://doi.org/10.1016/j.clgc.2022.08.006
Warrick, JI, Hu, W, Yamashita, H, Walter, V, Shuman, L, Craig, JM, Gellert, LL, Castro, MAA, Robertson, AG, Kuo, F, Ostrovnaya, I, Sarungbam, J, Chen, YB, Gopalan, A, Sirintrapun, SJ, Fine, SW, Tickoo, SK, Kim, K, Thomas, J, Karan, N, Gao, SP, Clinton, TN, Lenis, AT, Chan, TA, Chen, Z, Rao, M, Hollman, TJ, Li, Y, Socci, ND, Chavan, S, Viale, A, Mohibullah, N, Bochner, BH, Pietzak, EJ, Teo, MY, Iyer, G, Rosenberg, JE, Bajorin, DF, Kaag, M, Merrill, SB, Joshi, M, Adam, R, Taylor, JA, Clark, PE, Raman, JD, Reuter, VE, Chen, Y, Funt, SA, Solit, DB, DeGraff, DJ & Al-Ahmadie, HA 2022, 'Author Correction: FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation (Nature Communications, (2022), 13, 1, (6575), 10.1038/s41467-022-34251-3)', Nature communications, vol. 13, no. 1, 7920. https://doi.org/10.1038/s41467-022-35644-0
Sun, D, Hadjiiski, L, Alva, A, Zakharia, Y, Joshi, M, Chan, HP, Garje, R, Pomerantz, L, Elhag, D, Cohan, RH, Caoili, EM, Kerr, WT, Cha, KH, Kirova-Nedyalkova, G, Davenport, MS, Shankar, PR, Francis, IR, Shampain, K, Meyer, N, Barkmeier, D, Woolen, S, Palmbos, PL, Weizer, AZ, Samala, RK, Zhou, C & Matuszak, M 2022, 'Computerized Decision Support for Bladder Cancer Treatment Response Assessment in CT Urography: Effect on Diagnostic Accuracy in Multi-Institution Multi-Specialty Study', Tomography, vol. 8, no. 2, pp. 644-656. https://doi.org/10.3390/tomography8020054
on behalf of the COVID-19 and Cancer Consortium 2022, 'Demographics, Outcomes, and Risk Factors for Patients with Sarcoma and COVID-19: A CCC19-Registry Based Retrospective Cohort Study', Cancers, vol. 14, no. 17, 4334. https://doi.org/10.3390/cancers14174334
on behalf of the Global Society of Rare Genitourinary Tumors (GSRGT) and the International Bladder Cancer Group (IBCG) 2023, 'Disparities in Access to Novel Systemic Therapies in Patients With Urinary Tract Cancer: Propagating Access, Policies and Resources Uniformly', Clinical Genitourinary Cancer, vol. 21, no. 2, pp. 301-308. https://doi.org/10.1016/j.clgc.2022.10.002
Sun, D, Hadjiiski, L, Garje, R, Zakharia, Y, Pomerantz, L, Joshi, M, Alva, A, Chan, HP, Cohan, RH, Caoili, EM, Cha, KH, Kirova-Nedyalkova, G, Davenport, MS, Shankar, PR, Francis, IR, Shampain, K, Meyer, N, Barkmeier, D, Woolen, S, Palmbos, PL, Weizer, AZ, Samala, RK, Zhou, C & Matuszak, M 2022, Effect of computerized decision support on diagnostic accuracy and intra-observer variability in multi-institutional observer performance study for bladder cancer treatment response assessment in CT urography. in K Drukker & KM Iftekharuddin (eds), Medical Imaging 2022: Computer-Aided Diagnosis., 120330G, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 12033, SPIE, Medical Imaging 2022: Computer-Aided Diagnosis, Virtual, Online, 3/21/22. https://doi.org/10.1117/12.2611179
BLC2001 Study Group 2022, 'Efficacy and safety of erdafitinib in patients with locally advanced or metastatic urothelial carcinoma: long-term follow-up of a phase 2 study', The Lancet Oncology, vol. 23, no. 2, pp. 248-258. https://doi.org/10.1016/S1470-2045(21)00660-4
Weng, X, Shen, C, Van Scoy, LJ, Boltz, M, Joshi, M & Wang, L 2022, 'End-of-Life Costs of Cancer Patients With Alzheimer's Disease and Related Dementias in the U.S.', Journal of Pain and Symptom Management, vol. 64, no. 5, pp. 449-460. https://doi.org/10.1016/j.jpainsymman.2022.07.014
Warrick, JI, Hu, W, Yamashita, H, Walter, V, Shuman, L, Craig, JM, Gellert, LL, Castro, MAA, Robertson, AG, Kuo, F, Ostrovnaya, I, Sarungbam, J, Chen, YB, Gopalan, A, Sirintrapun, SJ, Fine, SW, Tickoo, SK, Kim, K, Thomas, J, Karan, N, Gao, SP, Clinton, TN, Lenis, AT, Chan, TA, Chen, Z, Rao, M, Hollman, TJ, Li, Y, Socci, ND, Chavan, S, Viale, A, Mohibullah, N, Bochner, BH, Pietzak, EJ, Teo, MY, Iyer, G, Rosenberg, JE, Bajorin, DF, Kaag, M, Merrill, SB, Joshi, M, Adam, R, Taylor, JA, Clark, PE, Raman, JD, Reuter, VE, Chen, Y, Funt, SA, Solit, DB, DeGraff, DJ & Al-Ahmadie, HA 2022, 'FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation', Nature communications, vol. 13, no. 1, 6575. https://doi.org/10.1038/s41467-022-34251-3
COVID-19 and Cancer Consortium 2022, 'Patients Recently Treated for B-lymphoid Malignancies Show Increased Risk of Severe COVID-19', Blood cancer discovery, vol. 3, no. 3, pp. 181-193. https://doi.org/10.1158/2643-3230.BCD-22-0013
Talukder, R, Makrakis, D, Diamantopoulos, LN, Carril-Ajuria, L, Castellano, D, De Kouchkovsky, I, Koshkin, VS, Park, JJ, Alva, A, Bilen, MA, Stewart, TF, McKay, RR, Santos, VS, Agarwal, N, Jain, J, Zakharia, Y, Morales-Barrera, R, Devitt, ME, Grant, M, Lythgoe, MP, Pinato, DJ, Nelson, A, Hoimes, CJ, Shreck, E, Gartrell, BA, Sankin, A, Tripathi, A, Zakopoulou, R, Bamias, A, Murgic, J, Fröbe, A, Rodriguez-Vida, A, Drakaki, A, Liu, S, Kumar, V, Lorenzo, GD, Joshi, M, Velho, PI, Buznego, LA, Duran, I, Moses, M, Barata, P, Sonpavde, G, Yu, EY, Wright, JL, Grivas, P & Khaki, AR 2022, 'Response and Outcomes to Immune Checkpoint Inhibitors in Advanced Urothelial Cancer Based on Prior Intravesical Bacillus Calmette-Guerin', Clinical Genitourinary Cancer, vol. 20, no. 2, pp. 165-175. https://doi.org/10.1016/j.clgc.2021.12.012
2021
Khaki, AR, Li, A, Diamantopoulos, LN, Miller, NJ, Carril-Ajuria, L, Castellano, D, De Kouchkovsky, I, Koshkin, V, Park, J, Alva, A, Bilen, MA, Stewart, T, Santos, V, Agarwal, N, Jain, J, Zakharia, Y, Morales-Barrera, R, Devitt, M, Nelson, A, Hoimes, CJ, Shreck, E, Gartrell, BA, Sankin, A, Tripathi, A, Zakopoulou, R, Bamias, A, Rodriguez-Vida, A, Drakaki, A, Liu, S, Kumar, V, Lythgoe, MP, Pinato, DJ, Murgic, J, Fröbe, A, Joshi, M, Isaacsson Velho, P, Hahn, N, Alonso Buznego, L, Duran, I, Moses, M, Barata, P, Galsky, MD, Sonpavde, G, Yu, EY, Shankaran, V, Lyman, GH & Grivas, P 2021, 'A New Prognostic Model in Patients with Advanced Urothelial Carcinoma Treated with First-line Immune Checkpoint Inhibitors', European Urology Oncology, vol. 4, no. 3, pp. 464-472. https://doi.org/10.1016/j.euo.2020.12.006
Schmidt, AL, Tucker, MD, Bakouny, Z, Labaki, C, Hsu, CY, Shyr, Y, Armstrong, AJ, Beer, TM, Bijjula, RR, Bilen, MA, Connell, CF, Dawsey, SJ, Faller, B, Gao, X, Gartrell, BA, Gill, D, Gulati, S, Halabi, S, Hwang, C, Joshi, M, Khaki, AR, Menon, H, Morris, MJ, Puc, M, Russell, KB, Shah, NJ, Sharifi, N, Shaya, J, Schweizer, MT, Steinharter, J, Wulff-Burchfield, EM, Xu, W, Zhu, J, Mishra, S, Grivas, P, Rini, BI, Warner, JL, Zhang, T, Choueiri, TK, Gupta, S & McKay, RR 2021, 'Association between Androgen Deprivation Therapy and Mortality among Patients with Prostate Cancer and COVID-19', JAMA network open, vol. 4, no. 11, e2134330. https://doi.org/10.1001/jamanetworkopen.2021.34330
Makrakis, D, Talukder, R, Diamantopoulos, LN, Carril-Ajuria, L, Castellano, D, De Kouchkovsky, I, Koshkin, VS, Park, JJ, Alva, A, Bilen, MA, Stewart, TF, McKay, RR, Santos, VS, Agarwal, N, Jain, J, Zakharia, Y, Morales-Barrera, R, Devitt, ME, Grant, M, Lythgoe, MP, Pinato, DJ, Nelson, A, Hoimes, CJ, Shreck, E, Gartrell, BA, Sankin, A, Tripathi, A, Zakopoulou, R, Bamias, A, Murgic, J, Fröbe, A, Rodriguez-Vida, A, Drakaki, A, Liu, S, Kumar, V, Di Lorenzo, G, Joshi, M, Isaacsson-Velho, P, Buznego, LA, Duran, I, Moses, M, Barata, P, Sonpavde, G, Yu, EY, Wright, JL, Grivas, P & Khaki, AR 2022, 'Association of prior local therapy and outcomes with programmed-death ligand-1 inhibitors in advanced urothelial cancer', BJU International, vol. 130, no. 5, pp. 592-603. https://doi.org/10.1111/bju.15603
Joshi, M, Holder, SL, Zhu, J, Zheng, H, Komanduri, S, Warrick, J, Yasin, H, Gajre, R, Jia, B, Drabick, JJ, DeGraff, DJ & Zakharia, Y 2022, 'Avelumab in Combination with Eribulin Mesylate in Metastatic Urothelial Carcinoma: BTCRC GU-051, a Phase 1b Study', European Urology Focus, vol. 8, no. 2, pp. 483-490. https://doi.org/10.1016/j.euf.2021.03.005
Nesterova, D, Zhu, J, Kramer, C, Vasekar, M, Truica, C, Joshi, A, Hayes, M, Kessler, J, Saunders, EFH, Drabick, JJ & Joshi, M 2022, 'Group-led creative writing and behavioural health in cancer: A randomised clinical trial', BMJ Supportive and Palliative Care, vol. 12, no. 1, pp. 91-98. https://doi.org/10.1136/bmjspcare-2020-002463
Esagian, SM, Khaki, AR, Diamantopoulos, LN, Carril-Ajuria, L, Castellano, D, De Kouchkovsky, I, Park, JJ, Alva, A, Bilen, MA, Stewart, TF, McKay, RR, Santos, VS, Agarwal, N, Jain, J, Zakharia, Y, Morales-Barrera, R, Devitt, ME, Nelson, A, Hoimes, CJ, Shreck, E, Gartrell, BA, Sankin, A, Tripathi, A, Zakopoulou, R, Bamias, A, Rodriguez-Vida, A, Drakaki, A, Liu, S, Kumar, V, Lythgoe, MP, Pinato, DJ, Murgic, J, Fröbe, A, Joshi, M, Isaacsson Velho, P, Hahn, N, Alonso Buznego, L, Duran, I, Moses, M, Barata, P, Galsky, MD, Sonpavde, G, Yu, EY, Msaouel, P, Koshkin, VS & Grivas, P 2021, 'Immune checkpoint inhibitors in advanced upper and lower tract urothelial carcinoma: a comparison of outcomes', BJU International, vol. 128, no. 2, pp. 196-205. https://doi.org/10.1111/bju.15324
Hadjiiski, L, Joshi, M, Alva, A, Chan, HP, Cohan, RH, Caoili, EM, Kirova-Nedyalkova, G, Davenport, MS, Shankar, PR, Francis, IR, Cha, KH, Samala, RK, Palmbos, PL & Weizer, AZ 2021, Multi-institutional observer performance study for bladder cancer treatment response assessment in CT urography with and without computerized decision support. in MA Mazurowski & K Drukker (eds), Medical Imaging 2021: Computer-Aided Diagnosis., 115971K, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 11597, SPIE, Medical Imaging 2021: Computer-Aided Diagnosis, Virtual, Online, United States, 2/15/21. https://doi.org/10.1117/12.2582331
KEYNOTE-361 Investigators 2021, 'Pembrolizumab alone or combined with chemotherapy versus chemotherapy as first-line therapy for advanced urothelial carcinoma (KEYNOTE-361): a randomised, open-label, phase 3 trial', The Lancet Oncology, vol. 22, no. 7, pp. 931-945. https://doi.org/10.1016/S1470-2045(21)00152-2
2020
The COVID-19 and Cancer Consortium 2020, 'A Systematic Framework to Rapidly Obtain Data on Patients with Cancer and COVID-19: CCC19 Governance, Protocol, and Quality Assurance', Cancer Cell, vol. 38, no. 6, pp. 761-766. https://doi.org/10.1016/j.ccell.2020.10.022
Joshi, M, Grivas, P, Mortazavi, A, Monk, P, Clinton, SK, Sue-Ann Woo, M, Holder, SL, Drabick, JJ & Yin, M 2020, 'Alterations of DNA damage response genes correlate with response and overall survival in anti-PD-1/PD-L1-treated advanced urothelial cancer', Cancer medicine, vol. 9, no. 24, pp. 9365-9372. https://doi.org/10.1002/cam4.3552
COVID-19 and Cancer Consortium 2020, 'Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study', The Lancet, vol. 395, no. 10241, pp. 1907-1918. https://doi.org/10.1016/S0140-6736(20)31187-9
Necchi, A, Madison, R, Pal, SK, Ross, JS, Agarwal, N, Sonpavde, G, Joshi, M, Yin, M, Miller, VA, Grivas, P, Chung, JH & Ali, SM 2021, 'Comprehensive Genomic Profiling of Upper-tract and Bladder Urothelial Carcinoma', European Urology Focus, vol. 7, no. 6, pp. 1339-1346. https://doi.org/10.1016/j.euf.2020.08.001
Miller, NJ, Khaki, AR, Diamantopoulos, LN, Bilen, MA, Santos, V, Agarwal, N, Morales-Barrera, R, Devitt, M, Nelson, A, Hoimes, CJ, Shreck, E, Assi, H, Gartrell, BA, Sankin, A, Rodriguez-Vida, A, Lythgoe, M, Pinato, DJ, Drakaki, A, Joshi, M, Isaacsson Velho, P, Hahn, N, Liu, S, Alonso Buznego, L, Duran, I, Moses, M, Jain, J, Murgic, J, Barata, P, Tripathi, A, Zakharia, Y, Galsky, MD, Sonpavde, G, Yu, EY, Lyman, GH & Grivas, P 2020, 'Histological Subtypes and Response to PD-1/PD-L1 Blockade in Advanced Urothelial Cancer: A Retrospective Study', Journal of Urology, vol. 204, no. 1, pp. 63-69. https://doi.org/10.1097/JU.0000000000000761
Khaki, AR, Li, A, Diamantopoulos, LN, Bilen, MA, Santos, V, Esther, J, Morales-Barrera, R, Devitt, M, Nelson, A, Hoimes, CJ, Shreck, E, Assi, H, Gartrell, BA, Sankin, A, Rodriguez-Vida, A, Lythgoe, M, Pinato, DJ, Drakaki, A, Joshi, M, Isaacsson Velho, P, Hahn, N, Liu, S, Alonso Buznego, L, Duran, I, Moses, M, Jain, J, Murgic, J, Baratam, P, Barata, P, Tripathi, A, Zakharia, Y, Galsky, MD, Sonpavde, G, Yu, EY, Shankaran, V, Lyman, GH & Grivas, P 2020, 'Impact of performance status on treatment outcomes: A real-world study of advanced urothelial cancer treated with immune checkpoint inhibitors', Cancer, vol. 126, no. 6, pp. 1208-1216. https://doi.org/10.1002/cncr.32645
Dudek, AZ, Liu, LC, Gupta, S, Logan, TF, Singer, EA, Joshi, M, Zakharia, YN, Lang, JM, Schwarz, JK, Al-Janadi, A & Alva, AS 2020, 'Phase Ib/II clinical trial of pembrolizumab with bevacizumab for metastatic renal cell carcinoma: BTCRC-GU14-003', Journal of Clinical Oncology, vol. 38, no. 11, pp. 1138-1145. https://doi.org/10.1200/JCO.19.02394
Yin, M, Grivas, P, Wang, QE, Mortazavi, A, Emamekhoo, H, Holder, SL, Drabick, JJ, Woo, MSA, Pal, S, Vasekar, M, Folefac, E, Clinton, SK, Monk, P & Joshi, M 2020, 'Prognostic Value of DNA Damage Response Genomic Alterations in Relapsed/Advanced Urothelial Cancer', Oncologist, vol. 25, no. 8, pp. 680-688. https://doi.org/10.1634/theoncologist.2019-0851