Chandrika Behura, MD - Penn State Cancer Institute
Researcher Profile
Chandrika Behura, MD
Associate Professor, Department of Pediatrics
Division of Hematology and Oncology
Penn State Neuroscience Institute
Division of Hematology and Oncology
Penn State Neuroscience Institute
Scientific Program:Experimental Therapeutics
Disease Teams:
Cancer Institute, Pediatric Cancer Team
Clinical Trials
A Phase 3 Randomized Controlled Trial Comparing Open vs Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Phase II Trial of Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma BCC022
ACCL1931: A Randomized Trial of Levocarnitine Prophylaxis to Prevent Asparaginase-Associated Hepatotoxicity in Adolescents and Young Adults Receiving Acute Lymphoblastic Leukemia Therapy
BCC021 Phase I/II study of Silmitasertib (CX-4945) in combination with chemotherapy in children and young adults with relapsed refractory solid tumors
Pediatric Acute Leukemia (PedAL) Screening Trial Developing New Therapies for Relapsed Leukemias
ARAR2221 A Phase 2 Study Using Chemoimmunotherapy with Gemcitabine, Cisplatin and Nivolumab in Newly Diagnosed Nasopharyngeal Carcinoma (NPC)
A Prospective Phase 3 Study of Patients with Newly Diagnosed Very Low-risk and Low-risk Fusion Negative Rhabdomyosarcoma
A Dose Escalation Study Using Difluoromethylornithine (DFMO) and AMXT-1501 followed by a Randomized Controlled Trial of DFMO with or without AMXT-1501 for Neuroblastoma, CNS Tumors, and Sarcomas
AHOD2131 A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy with Immuno-oncology Therapy for Children and Adults with Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma
Recent Publications
2025
Rajaiah, R, Daniyal, M, Shanmugam, MP, Valensi, H, Duke, K, Mercer, K, Klink, M, Lanza, M, Uzun, Y, Huang, S, Dovat, S & Behura, CG 2025, 'CK2α Deletion in the Hematopoietic Compartment Shows a Mild Alteration in Terminally Differentiated Cells and the Expansion of Stem Cells', Cells, vol. 14, no. 13, 963. https://doi.org/10.3390/cells14130963
2024
Zhang, L, Muscat, JE, Chinchilli, VM & Behura, CG 2024, 'Trends in Cancer Incidence and Mortality in US Adolescents and Young Adults, 2016–2021', Cancers, vol. 16, no. 18, 3153. https://doi.org/10.3390/cancers16183153
2023
Bogush, D, Schramm, J, Ding, Y, He, B, Singh, C, Sharma, A, Tukaramrao, DB, Iyer, S, Desai, D, Nalesnik, G, Hengst, J, Bhalodia, R, Gowda, C & Dovat, S 2023, 'Signaling pathways and regulation of gene expression in hematopoietic cells', Advances in Biological Regulation, vol. 88, 100942. https://doi.org/10.1016/j.jbior.2022.100942
2022
Wills, C, Mercer, K, Malysz, J, Galvis, LR & Gowda, C 2022, 'Chronic Generalized Lymphadenopathy in a Child—Progressive Transformation of Germinal Centers (PTGC)', Children, vol. 9, no. 2, 214. https://doi.org/10.3390/children9020214
Dovat, S, Gowda, C, Mailman, RB, Parent, LJ & Huang, X 2022, 'Clinician-Scientist Faculty Mentoring Program (FAME) – A New Inclusive Training Model at Penn State Increases Scholarly Productivity and Extramural Grant Funding', Advances in Medical Education and Practice, vol. 13, pp. 1039-1050. https://doi.org/10.2147/AMEP.S365953
Gowda, C, Purandare, A, Mercer, K, Duke, K & Dovat, S 2022, 'Novel Casein Kinase II (CK2) inhibitor BMS-135 shows significant in vivo anti-leukemia effect', European Journal of Cancer, vol. 174, pp. S29. https://doi.org/10.1016/S0959-8049(22)00879-6