Hui Yang, Gary and Sheila Bello Chair and Professor - Penn State Cancer Institute
Researcher Profile
Hui Yang, Gary and Sheila Bello Chair and Professor
Professor, Harold and Inge Marcus Department of Industrial and Manufacturing Engineering
Scientific Program:Cancer Control
Recent Publications
2026
Mekulu, K, Aqlan, F & Yang, H 2026, 'A transparent four-feature speech model for depression screening applicable across clinical and community settings, including assisted-living environments', Frontiers in Digital Health, vol. 7, 1675103. https://doi.org/10.3389/fdgth.2025.1675103
Zhang, S & Yang, H 2026, 'Dual Generative Adversarial Networks for Neighborhood Learning and Prediction of Melt-Pool Dynamics in Additive Manufacturing', Journal of Computing and Information Science in Engineering, vol. 26, no. 3, 031001. https://doi.org/10.1115/1.4070797
Kuo, T & Yang, H 2026, 'Generative adversarial networks for resilient design of manufacturing systems', IISE Transactions. https://doi.org/10.1080/24725854.2026.2642363
Alomran, O & Yang, H 2026, Smart Automation and Robotics in Healthcare: Transforming Hospital Material Handling Systems. in Internet of Things. Internet of Things, vol. Part F1652, Springer Science and Business Media Deutschland GmbH, pp. 291-309. https://doi.org/10.1007/978-3-032-02709-2_13
Liu, R & Yang, H 2026, 'Wavelet Gaussian process for multi-scale monitoring of imaging data', IISE Transactions. https://doi.org/10.1080/24725854.2026.2632144
2025
Mekulu, K, Aqlan, F & Yang, H 2025, 'Agentic artificial intelligence in cognitive screening: A translational roadmap for dementia care', Journal of Alzheimer's Disease Reports, vol. 9. https://doi.org/10.1177/25424823251407989
Mekulu, K, Aqlan, F & Yang, H 2025, 'CharMark: character-level Markov modeling for interpretable linguistic biomarkers of cognitive decline', Frontiers in Digital Health, vol. 7, 1659366. https://doi.org/10.3389/fdgth.2025.1659366
Mekulu, K, Aqlan, F & Yang, H 2025, 'Character-level linguistic biomarkers for precision assessment of cognitive decline: a symbolic recurrence approach', Frontiers in Aging Neuroscience, vol. 17, 1681124. https://doi.org/10.3389/fnagi.2025.1681124
Lee, H & Yang, H 2025, 'Cognitive Digital Twin for Multiobjective Production Scheduling', Journal of Manufacturing Science and Engineering, vol. 147, no. 9, 091004. https://doi.org/10.1115/1.4068980
Begum, R, Hamado, N, Aqlan, F, Zhao, R, Yang, H, Saleem, J, DeCaro, M & Murphy, K 2025, 'Collaborative virtual learning factory for advanced manufacturing: investigating user experience and team dynamics', Manufacturing Letters, vol. 46, pp. 128-132. https://doi.org/10.1016/j.mfglet.2025.11.002
Ye, Z, Cai, Z, Yang, H, Si, S & Zhao, QQ 2025, 'Enhancing adaptive failure risk prognosis for cutting tools in heterogeneous working environments: A comprehensive modeling framework', Expert Systems With Applications, vol. 280, 127527. https://doi.org/10.1016/j.eswa.2025.127527
Begum, R, Aqlan, F, Decaro, MS, Yang, H, Zhao, R, Saleem, JJ & Murphy, PK 2025, 'Exploring Human-Human Teaming and Human-Machine Interaction in a Collaborative Virtual Learning Factory', ASEE Annual Conference and Exposition, Conference Proceedings. https://doi.org/10.18260/1-2--56511
Kuo, T & Yang, H 2025, Hierarchical Blockchain for Mapping Manufacturing Process Flow. in 2025 IEEE 21st International Conference on Automation Science and Engineering, CASE 2025. IEEE International Conference on Automation Science and Engineering, IEEE Computer Society, pp. 2657-2662, 21st IEEE International Conference on Automation Science and Engineering, CASE 2025, Los Angeles, United States, 8/17/25. https://doi.org/10.1109/CASE58245.2025.11164079
Lee, H & Yang, H 2025, MULTI-AGENT ARTIFICIAL INTELLIGENCE TO SELF-ORGANIZE MACHINE NETWORKS FOR RESILIENT MANUFACTURING. in Functional Devices/Bioinspired Structures; Sustainability; Semiconductor Manufacturing; Surface Engineering; Clean Energy and E-Mobility Manufacturing; Machining and Deformation Processes; Welding and Joining Processes of Advanced Materials and Structures; Equipment Design, Control and Automation; Human Integration to Smart Manufacturing Systems; Thin Films and Coatings; Meso, Micro, Nano Subtractive and Formative Manufacturing; Explainable AI for Knowledge Discovery., V002T20A006, Proceedings of ASME 2025 20th International Manufacturing Science and Engineering Conference, MSEC 2025, vol. 2, American Society of Mechanical Engineers (ASME), ASME 2025 20th International Manufacturing Science and Engineering Conference, MSEC 2025, Greenville, United States, 6/23/25. https://doi.org/10.1115/MSEC2025-155761
Kuo, T & Yang, H 2025, 'Multi-layer encrypted learning for distributed healthcare analytics', Scientific reports, vol. 15, no. 1, 39442. https://doi.org/10.1038/s41598-025-23140-6
Ye, Z, Wang, L, Yang, H & Cai, Z 2025, 'Multivariate failure prognosis of cutting tools under heterogeneous operating conditions', Advanced Engineering Informatics, vol. 65, 103198. https://doi.org/10.1016/j.aei.2025.103198
Liu, R & Yang, H 2025, Optimizing Network Simulation of Cardiac Electrical Dynamics. in 2025 IEEE 21st International Conference on Automation Science and Engineering, CASE 2025. IEEE International Conference on Automation Science and Engineering, IEEE Computer Society, pp. 814-819, 21st IEEE International Conference on Automation Science and Engineering, CASE 2025, Los Angeles, United States, 8/17/25. https://doi.org/10.1109/CASE58245.2025.11163831
Mekulu, K, Aqlan, F & Yang, H 2025, 'Reimagining dementia screening: A stakeholder-informed perspective on artificial intelligence, digital biomarkers, and real-world implementation', Journal of Alzheimer's Disease Reports, vol. 9. https://doi.org/10.1177/25424823251395310
Alomran, O & Yang, H 2025, Risk-Averse Autonomous Material Handling in Healthcare Systems. in 2025 IEEE 21st International Conference on Automation Science and Engineering, CASE 2025. IEEE International Conference on Automation Science and Engineering, IEEE Computer Society, pp. 1050-1055, 21st IEEE International Conference on Automation Science and Engineering, CASE 2025, Los Angeles, United States, 8/17/25. https://doi.org/10.1109/CASE58245.2025.11163993
Peng, X, Liu, R & Yang, H 2025, SCOUT: Spatiotemporal Coverage for Optimal Unmanned Tasking. in 2025 IEEE 21st International Conference on Automation Science and Engineering, CASE 2025. IEEE International Conference on Automation Science and Engineering, IEEE Computer Society, pp. 2103-2108, 21st IEEE International Conference on Automation Science and Engineering, CASE 2025, Los Angeles, United States, 8/17/25. https://doi.org/10.1109/CASE58245.2025.11163795
Liu, R & Yang, H 2025, 'Self-organizing network simulation of cardiac contraction dynamics', Chaos, vol. 35, no. 12, 121105. https://doi.org/10.1063/5.0305451
Liu, R & Yang, H 2025, 'Self-organizing network simulation of cardiac electrical dynamics', Chaos, vol. 35, no. 4, 041102. https://doi.org/10.1063/5.0261019
Mekulu, K, Aqlan, F & Yang, H 2025, 'The mild cognitive impairment window for optimal Alzheimer's disease intervention', Journal of Alzheimer's Disease Reports, vol. 9. https://doi.org/10.1177/25424823251370768
Yang, H, Aqlan, F & Zhao, R 2025, 'Toward Smart Manufacturing Metaverse via Digital Twinning in Extended Reality', Journal of Computing and Information Science in Engineering, vol. 25, no. 12, 120810. https://doi.org/10.1115/1.4070437
2024
Kim, H, Hartleb, T, Bello, K, Aqlan, F, Zhao, R & Yang, H 2024, 'Behavioral Modeling of Collaborative Problem Solving in Multiplayer Virtual Reality Manufacturing Simulation Games', Journal of Computing and Information Science in Engineering, vol. 24, no. 3, 031006. https://doi.org/10.1115/1.4063089
Zhang, S, Yang, H, Yang, Z & Lu, Y 2024, 'Engineering-Guided Deep Learning of Melt-Pool Dynamics for Additive Manufacturing Quality Monitoring', Journal of Computing and Information Science in Engineering, vol. 24, no. 10, 101002. https://doi.org/10.1115/1.4066026
Kuo, T & Yang, H 2024, 'Federated Learning on Distributed and Encrypted Data for Smart Manufacturing', Journal of Computing and Information Science in Engineering, vol. 24, no. 7, 071007. https://doi.org/10.1115/1.4065571
Shi, X, Lee, H & Yang, H 2024, Multi-agent Modeling of Human Traffic Dynamics for Rapid Response to Public Emergency in Spatial Networks. in 2024 IEEE 20th International Conference on Automation Science and Engineering, CASE 2024. IEEE International Conference on Automation Science and Engineering, IEEE Computer Society, pp. 374-380, 20th IEEE International Conference on Automation Science and Engineering, CASE 2024, Bari, Italy, 8/28/24. https://doi.org/10.1109/CASE59546.2024.10711522
Zhang, S, Lu, Y & Yang, H 2025, 'Multiscale basis modeling of 3D melt-pool morphological variations for manufacturing process monitoring', International Journal of Advanced Manufacturing Technology, vol. 136, no. 9, pp. 4055-4066. https://doi.org/10.1007/s00170-024-13377-2
Lee, H, Finke, D & Yang, H 2024, 'Privacy-Preserving Neural Networks for Smart Manufacturing', Journal of Computing and Information Science in Engineering, vol. 24, no. 7, 071002. https://doi.org/10.1115/1.4063728
Liu, R & Yang, H 2024, 'Self-organizing network representation of human heart', Chaos, vol. 34, no. 12. https://doi.org/10.1063/5.0243391
2023
Hanchate, A, Dave, PS, Verma, A, Tiwari, A, Mishra, CS, Kumara, SRT, Srivastava, A, Yang, H, Narayanan, V, Sampson, JM, Kandemir, MT, Lee, KH, Pugh, TM, Jorden, A, Natarajan, G, Sagapuram, D & Bukkapatnam, STS 2023, 'A Graphical Representation of Sensor Mapping for Machine Tool Fault Monitoring and Prognostics for Smart Manufacturing', Smart and Sustainable Manufacturing Systems, vol. 7, no. 1, pp. 82-110. https://doi.org/10.1520/SSMS20220031
Lee, H & Yang, H 2023, DIGITAL TWIN SIMULATION AND OPTIMIZATION OF MANUFACTURING PROCESS FLOWS. in Manufacturing Equipment and Automation; Manufacturing Processes; Manufacturing Systems; Nano/Micro/Meso Manufacturing; Quality and Reliability., v002t07a013, Proceedings of ASME 2023 18th International Manufacturing Science and Engineering Conference, MSEC 2023, vol. 2, American Society of Mechanical Engineers, ASME 2023 18th International Manufacturing Science and Engineering Conference, MSEC 2023, New Brunswick, United States, 6/12/23. https://doi.org/10.1115/msec2023-105613
Lee, H & Yang, H 2023, 'Digital Twinning and Optimization of Manufacturing Process Flows', Journal of Manufacturing Science and Engineering, vol. 145, no. 11, 111008. https://doi.org/10.1115/1.4063234
Krall, A, Finke, D & Yang, H 2024, 'Distributed cryptosystem for service-oriented smart manufacturing', IISE Transactions, vol. 56, no. 12, pp. 1346-1359. https://doi.org/10.1080/24725854.2023.2291728
Roh, BM, Simpson, TW, Yang, H, Kumara, SRT, Witherell, P & Jones, AT 2023, 'Ensuring Quality in Metal Additive Manufacturing Through a V-Model Framework', IEEE Access, vol. 11, pp. 123807-123819. https://doi.org/10.1109/ACCESS.2023.3327054
Hartleb, T, Kim, H, Zhao, R, Aqlan, F & Yang, H 2023, 'Exploring Magic Interactions for Collaboration in Virtual Reality Learning Factory', ASEE Annual Conference and Exposition, Conference Proceedings.
Alomran, O, Qiu, R & Yang, H 2023, 'Hierarchical clinical decision support for breast cancer care empowered with Bayesian networks', Digital Transformation and Society, vol. 2, no. 2, pp. 163-178. https://doi.org/10.1108/DTS-11-2022-0063
Ye, Z, Cai, Z, Yang, H, Si, S & Zhou, F 2023, 'Joint optimization of maintenance and quality inspection for manufacturing networks based on deep reinforcement learning', Reliability Engineering and System Safety, vol. 236, 109290. https://doi.org/10.1016/j.ress.2023.109290
Yang, H, Reijonen, J & Revuelta, A 2023, MULTI-RESOLUTION QUALITY INSPECTION FOR ADDITIVE MANUFACTURING. in Additive Manufacturing; Advanced Materials Manufacturing; Biomanufacturing; Life Cycle Engineering., v001t01a011, Proceedings of ASME 2023 18th International Manufacturing Science and Engineering Conference, MSEC 2023, vol. 1, American Society of Mechanical Engineers, ASME 2023 18th International Manufacturing Science and Engineering Conference, MSEC 2023, New Brunswick, United States, 6/12/23. https://doi.org/10.1115/msec2023-104348
Kim, H, Yang, H, Ednie, AR & Bennett, ES 2024, 'Model-guided concurrent data assimilation for calibrating cardiac ion-channel kinetics', IISE Transactions on Healthcare Systems Engineering, vol. 14, no. 2, pp. 153-166. https://doi.org/10.1080/24725579.2023.2239271
Liu, R & Yang, H 2023, 'Multimodal probabilistic modeling of melt pool geometry variations in additive manufacturing', Additive Manufacturing, vol. 61, 103375. https://doi.org/10.1016/j.addma.2022.103375
Yang, H, Reijonen, J & Revuelta, A 2023, 'Multiresolution Quality Inspection of Layerwise Builds for Metal 3D Printer and Scanner', Journal of Manufacturing Science and Engineering, vol. 145, no. 10, 101004. https://doi.org/10.1115/1.4057013
Chen, CB, Wang, Y, Fu, X & Yang, H 2023, 'Recurrence Network Analysis of Histopathological Images for the Detection of Invasive Ductal Carcinoma in Breast Cancer', IEEE/ACM Transactions on Computational Biology and Bioinformatics, vol. 20, no. 5, pp. 3234-3244. https://doi.org/10.1109/TCBB.2023.3282798
2022
Sloan, HA, Zhao, R, Aqlan, F, Yang, H & Zhu, R 2022, 'Adaptive Virtual Assistant for Virtual Reality-based Remote Learning', ASEE Annual Conference and Exposition, Conference Proceedings.
Zhu, R, Aqlan, F, Zhao, R, Yang, H & Li, Y 2022, Advanced Modeling of Problem-solving Behavior in Virtual Reality Manufacturing Environments. in K Ellis, W Ferrell & J Knapp (eds), IISE Annual Conference and Expo 2022. IISE Annual Conference and Expo 2022, Institute of Industrial and Systems Engineers, IISE, IISE Annual Conference and Expo 2022, Seattle, United States, 5/21/22.
Yang, H, Zhang, S, Liu, R, Krall, A, Wang, Y, Ventura, M & Deflitch, C 2022, Epidemic Informatics and Control: A Review from System Informatics to Epidemic Response and Risk Management in Public Health. in H Yang, R Qiu & W Chen (eds), AI and Analytics for Public Health - Proceedings of the 2020 INFORMS International Conference on Service Science. Springer Proceedings in Business and Economics, Springer Science and Business Media B.V., pp. 1-58, INFORMS International Conference on Service Science, ICSS 2020, Virtual, Online, 12/19/20. https://doi.org/10.1007/978-3-030-75166-1_1
Su, S, Xue, T, Chen, Y & Yang, H 2023, 'Harmonic control of a dual-valve hydraulic servo system with dynamically allocated flows', Asian Journal of Control, vol. 25, no. 3, pp. 1939-1956. https://doi.org/10.1002/asjc.2812
Ye, Z, Si, S, Yang, H, Cai, Z & Zhou, F 2022, 'Machine and Feedstock Interdependence Modeling for Manufacturing Networks Performance Analysis', IEEE Transactions on Industrial Informatics, vol. 18, no. 8, pp. 5067-5076. https://doi.org/10.1109/TII.2021.3129003
Roh, BM, Kumara, SRT, Yang, H, Simpson, TW, Witherell, P, Jones, AT & Lu, Y 2022, 'Ontology Network-Based In-Situ Sensor Selection for Quality Management in Metal Additive Manufacturing', Journal of Computing and Information Science in Engineering, vol. 22, no. 6, 060905. https://doi.org/10.1115/1.4055853
Zhu, R, Aqlan, F & Yang, H 2022, Optimal Resource Allocation for Coverage Control of City Crimes. in H Yang, R Qiu & W Chen (eds), AI and Analytics for Public Health - Proceedings of the 2020 INFORMS International Conference on Service Science. Springer Proceedings in Business and Economics, Springer Science and Business Media B.V., pp. 149-161, INFORMS International Conference on Service Science, ICSS 2020, Virtual, Online, 12/19/20. https://doi.org/10.1007/978-3-030-75166-1_9
Zhu, R, Aqlan, F, Zhao, R & Yang, H 2022, 'Sensor-based modeling of problem-solving in virtual reality manufacturing systems', Expert Systems With Applications, vol. 201, 117220. https://doi.org/10.1016/j.eswa.2022.117220
Kim, H, Yang, H, Ednie, AR & Bennett, ES 2022, 'Simulation Modeling of Reduced Glycosylation Effects on Potassium Channels of Mouse Cardiomyocytes', Frontiers in Physiology, vol. 13, 816651. https://doi.org/10.3389/fphys.2022.816651
Liu, R & Yang, H 2022, 'Spatial Tessellation of Infectious Disease Spread for Epidemic Decision Support', IEEE Robotics and Automation Letters, vol. 7, no. 1, pp. 626-633. https://doi.org/10.1109/LRA.2021.3131699
Yang, H, Zhang, S, Lu, Y, Witherell, P & Kumara, S 2022, 'Spatiotemporal Monitoring of Melt-Pool Variations in Metal-Based Additive Manufacturing', IEEE Robotics and Automation Letters, vol. 7, no. 3, pp. 8249-8256. https://doi.org/10.1109/LRA.2022.3187540
Krall, A, Finke, D & Yang, H 2023, 'Virtual sensing network for statistical process monitoring', IISE Transactions, vol. 55, no. 11, pp. 1103-1117. https://doi.org/10.1080/24725854.2022.2148779