Researcher Profile

Researcher Profile

Leila Tchelebi, MD

Leila Tchelebi, MD

Assistant Professor, Department of Radiation Oncology
Disease Teams:
Gastrointestinal Cancer
Head and Neck Cancer
Liver, Pancreas and Foregut Cancer

Research Interests

Dr. Leila Tchelebi’s research interests have an emphasis on cancers of the gastrointestinal tract. She has co-authored a textbook chapter on GI cancers and written a number of review papers on the role of radiation therapy in upper GI cancers. Her ongoing research is aimed at improving outcomes for patients with pancreatic cancer, for which efforts are needed to improve patient outcomes. She is optimistic that ongoing efforts will one day improve cure rates for this and other GI cancers. 

  • Neoplasms
  • Radiotherapy
  • Therapeutics
  • Systematic Reviews
  • Survival
  • Radiation
  • Pancreatic Neoplasms
  • Epidemiology
  • Meta-Analysis
  • Neoplasm Metastasis
  • Liver
  • Radiosurgery

Clinical Trials

A Phase 3, Randomized, Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of Stereotactic Body Radiotherapy (SBRT) with or without Pembrolizumab (MK-3475) in Participants with Medically Inoperable Stages I or IIA Non Small Cell Lung Cancer (NSCLC)(KEYNOTE-867) MK 3475-867
NRG-HN005 - A Randomized Phase II/III Trial of De-intensified Radiation Therapy for Patients with Early-Stage, P16-Positive, Non-Smoking Associated Oropharyngeal Cancer

Recent Publications


Anker, CJ, Dragovic, J, Herman, JM, Bianchi, NA, Goodman, KA, Jones, WE, Kennedy, TJ, Kumar, R, Lee, P, Russo, S, Sharma, N, Small, W, Suh, WW, Tchelebi, LT & Jabbour, SK 2021, 'Executive Summary of the American Radium Society Appropriate Use Criteria for Operable Esophageal and Gastroesophageal Junction Adenocarcinoma: Systematic Review and Guidelines', International Journal of Radiation Oncology Biology Physics, vol. 109, no. 1, pp. 186-200.


Allenby, TH, Crenshaw, ML, Mathis, K, Champ, CE, Simone, NL, Schmitz, KH, Tchelebi, LT & Zaorsky, NG 2020, 'A systematic review of home-based dietary interventions during radiation therapy for cancer', Technical Innovations and Patient Support in Radiation Oncology, vol. 16, pp. 10-16.
Tchelebi, LT, Lehrer, EJ, Trifiletti, DM, Sharma, NK, Gusani, NJ, Crane, CH & Zaorsky, NG 2020, 'Conventionally fractionated radiation therapy versus stereotactic body radiation therapy for locally advanced pancreatic cancer (CRiSP): An international systematic review and meta-analysis', Cancer, vol. 126, no. 10, pp. 2120-2131.
Horn, SR, Stoltzfus, KC, Lehrer, EJ, Dawson, LA, Tchelebi, L, Gusani, NJ, Sharma, NK, Chen, H, Trifiletti, DM & Zaorsky, NG 2020, 'Epidemiology of liver metastases', Cancer Epidemiology, vol. 67, 101760.
Tchelebi, LT, Haustermans, K, Scorsetti, M, Hosni, A, Huguet, F, Hawkins, MA, Dawson, LA & Goodman, KA 2020, 'Recommendations for the use of radiation therapy in managing patients with gastrointestinal malignancies in the era of COVID-19', Radiotherapy and Oncology, vol. 148, pp. 194-200.
Tchelebi, LT, Zaorsky, NG, Rosenberg, JC, Sharma, NK, Tuanquin, LC, MacKley, HB & Ellis, RJ 2020, 'Reducing the Toxicity of Radiotherapy for Pancreatic Cancer with Magnetic Resonance-guided Radiotherapy', Toxicological Sciences, vol. 175, no. 1, pp. 19-23.
Tchelebi, LT & Goodman, K 2020, 'Response to, “Role of neoadjuvant radiochemotherapy for esophageal cancers over pre/peri-operative chemotherapy in the era of COVID-19 and beyond”', Radiotherapy and Oncology.
Lehrer, EJ, Singh, R, Wang, M, Chinchilli, VM, Trifiletti, DM, Ost, P, Siva, S, Meng, MB, Tchelebi, L & Zaorsky, N 2020, 'Safety and Survival Rates Associated with Ablative Stereotactic Radiotherapy for Patients with Oligometastatic Cancer: A Systematic Review and Meta-analysis', JAMA Oncology.


Zaorsky, NG, Zhang, Y, Walter, V, Tchelebi, LT, Chinchilli, VM & Gusani, NJ 2019, 'Clinical trial accrual at initial course of therapy for cancer and its impact on survival', JNCCN Journal of the National Comprehensive Cancer Network, vol. 17, no. 11, pp. 1309-1316.
Tchelebi, L & Sharma, NK 2019, 'Selective Internal Radiation Therapy in the Multidisciplinary Management of Liver Metastases From Colorectal Carcinoma', Seminars in Nuclear Medicine, vol. 49, no. 3, pp. 182-188.
Zaorsky, NG, Zhang, Y, Tchelebi, LT, Mackley, HB, Chinchilli, VM & Zacharia, BE 2019, 'Stroke among cancer patients', Nature communications, vol. 10, no. 1, 5172.


Yee, NS, Lengerich, EJ, Schmitz, KH, Maranki, JL, Gusani, NJ, Tchelebi, L, Mackley, HB, Krok, KL, Baker, MJ, de Boer, C & Yee, JD 2018, 'Frontiers in gastrointestinal oncology: Advances in multi-disciplinary patient care', Biomedicines, vol. 6, no. 2, 64.
Tchelebi, L, Zaorsky, N & Mackley, H 2018, 'Stereotactic body radiation therapy in the management of upper GI malignancies', Biomedicines, vol. 6, no. 1, 7.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)